| Title: |
Reinfection with Ascaris lumbricoides after chemotherapy: a comparative study in three villages with varying sanitation |
| Authors: |
Henry, Fitzroy J. |
| Publisher Information: |
Oxford University Press |
| Publication Year: |
1988 |
| Collection: |
HighWire Press (Stanford University) |
| Subject Terms: |
Articles |
| Description: |
This study examined the effect of the 2 major means of control of Ascaris lumbricoides —chemotherapy and sanitation. About 200 pre-school Caribbean children living in 3 villages with varying sanitation were studied by quantitative stool examination for the presence of the eggs of helminths. Children with Ascaris eggs were treated with piperazine. Over a 2-year period this procedure was repeated after every 6 months of natural re-infection. Results showed that (i) the rate of reinfection was on average 20% higher than the rate of new infection; (ii) there was a highly significant correlation between the result of children's initial stool examination and that 6 months later; (iii) children with high Ascaris egg counts also frequently had high Trichuris egg counts; (iv) during the 6-month intervals, 36% of the infected children were not reinfected after treatment; the difference in reinfection rates between villages with and without sanitation was 48%. Regression analysis indicated that, after several socio-economic variables were controlled, only sanitation and crowding remained significantly associated with reinfection. The implications of these findings in formulating control strategies are discussed. |
| Document Type: |
text |
| File Description: |
text/html |
| Language: |
English |
| Relation: |
http://trstmh.oxfordjournals.org/cgi/content/short/82/3/460; http://dx.doi.org/10.1016/0035-9203(88)90162-9 |
| DOI: |
10.1016/0035-9203(88)90162-9 |
| Availability: |
http://trstmh.oxfordjournals.org/cgi/content/short/82/3/460; https://doi.org/10.1016/0035-9203(88)90162-9 |
| Rights: |
Copyright (C) 1988, Royal Society of Tropical Medicine and Hygiene |
| Accession Number: |
edsbas.5BCCCBD0 |
| Database: |
BASE |