| Title: |
Multi-institutional prospective observational study of radiotherapy for metastatic bone tumor |
| Authors: |
Harada, Hideyuki; Shikama, Naoto; Notsu, Akifumi; Shirato, Hiroki; Yamada, Kazunari; Uezono, Haruka; Koide, Yutaro; Kubota, Hikaru; Yamazaki, Takuya; Ito, Kei; Heianna, Joichi; Okada, Yukinori; Tonari, Ayako; Katoh, Norio; Wada, Hitoshi; Ejima, Yasuo; Yoshida, Kayo; Kosugi, Takashi; Takahashi, Shigeo; Komiyama, Takafumi; Uchida, Nobue; Miwa, Misako; Watanabe, Miho; Nagakura, Hisayasu; Ikeda, Hiroko; Saito, Tetsuo; Asakawa, Isao; Takahashi, Takeo; Shigematsu, Naoyuki |
| Contributors: |
Ministry of Health, Labor, and Welfare of Japan |
| Source: |
Journal of Radiation Research ; volume 65, issue 5, page 701-711 ; ISSN 0449-3060 1349-9157 |
| Publisher Information: |
Oxford University Press (OUP) |
| Publication Year: |
2024 |
| Description: |
Purpose of this study is to evaluate patient characteristics, treatments and outcomes in bone metastasis radiotherapy practice. Patients for whom radiotherapy for bone metastasis was planned at 26 institutions in Japan between December 2020 and March 2021 were consecutively registered in this prospective, observational study. Study measures included patient characteristics, pain relief, skeletal-related events (SREs), overall survival and incidence of radiation-related adverse events. Pain was evaluated using a numerical rating scale (NRS) from 0 to 10. Irradiated dose was analyzed by the biologically effective dose (BED) assuming α/β = 10. Overall, 232 patients were registered; 224 patients and 302 lesions were fully analyzed. Eastern Cooperative Oncology Group Performance Status was 0/1/2/3/4 in 23%/38%/22%/13%/4%; 59% of patients had spinal metastases and 84% had painful lesions (NRS ≥ 2). BED was |
| Document Type: |
article in journal/newspaper |
| Language: |
English |
| DOI: |
10.1093/jrr/rrae060 |
| Availability: |
https://doi.org/10.1093/jrr/rrae060; https://academic.oup.com/jrr/article-pdf/65/5/701/59277120/rrae060.pdf |
| Rights: |
https://creativecommons.org/licenses/by/4.0/ |
| Accession Number: |
edsbas.5BE05E71 |
| Database: |
BASE |