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HIV Malaria Co-Infection Is Associated with Atypical Memory B Cell Expansion and a Reduced Antibody Response to a Broad Array of Plasmodium falciparum Antigens in Rwandan Adults

Title: HIV Malaria Co-Infection Is Associated with Atypical Memory B Cell Expansion and a Reduced Antibody Response to a Broad Array of Plasmodium falciparum Antigens in Rwandan Adults
Authors: Subramaniam, Krishanthi; Skinner, Jeff; Ivan, Emil; Mutimura, Eugene; Kim, Ryung S.; Feintuch, Catherine M.; Portugal, Silvia; Anastos, Kathryn; Crompton, Peter D.; Daily, Johanna P.
Source: PLoS ONE, Vol 10, Issue 4, e0124412.
Publisher Information: Public Library of Science
Publication Year: 2015
Collection: LSTM Online Archive (Liverpool School of Tropical Medicine)
Subject Terms: QW 573 Antigens; QW 575 Antibodies; QX 135 Plasmodia; WA 395 Health in developing countries; WC 503 Acquired immunodeficiency syndrome. HIV infections; WC 750 Malaria
Description: HIV infected individuals in malaria endemic areas experience more frequent and severe malaria episodes compared to non HIV infected. This clinical observation has been linked to a deficiency in antibody responses to Plasmodium falciparum antigens; however, prior studies have only focused on the antibody response to
Document Type: article in journal/newspaper
File Description: text
Language: English
Relation: https://archive.lstmed.ac.uk/5159/1/Plos_ONE_10_4_e0124412.pdf; Subramaniam, Krishanthi, Skinner, Jeff, Ivan, Emil, Mutimura, Eugene, Kim, Ryung S., Feintuch, Catherine M., Portugal, Silvia, Anastos, Kathryn, Crompton, Peter D. and Daily, Johanna P. (2015) 'HIV Malaria Co-Infection Is Associated with Atypical Memory B Cell Expansion and a Reduced Antibody Response to a Broad Array of Plasmodium falciparum Antigens in Rwandan Adults'. PLoS ONE, Vol 10, Issue 4, e0124412.
DOI: 10.1371/journal.pone.0124412
Availability: https://archive.lstmed.ac.uk/5159/; https://doi.org/10.1371/journal.pone.0124412; https://archive.lstmed.ac.uk/5159/1/Plos_ONE_10_4_e0124412.pdf
Rights: cc_public_domain
Accession Number: edsbas.5D02006C
Database: BASE