| Title: |
Low plasma bicarbonate predicts poor outcome of cerebral malaria in Nigerian children |
| Authors: |
S Oguche; SI Omokhodion; AA Adeyemo; PE Olumese |
| Source: |
West African Journal of Medicine; Vol 21, No 4 (2002); 276-279 |
| Publisher Information: |
West African Journal of Medicine |
| Publication Year: |
2004 |
| Collection: |
AJOL - African Journals Online |
| Subject Terms: |
Cerebral malaria; Electrolyte imbalances; Acidosis; Children; Nigeria |
| Description: |
Malaria remains a major cause of morbidity and mortality in many sub Saharan countries and cerebral malaria is widely recognised as one of its most fatal forms. We studied the predictive value of routine biochemical laboratory indices in predicting the outcome of cerebral malaria in 50 Nigerian children ages 9 months to 6 years with cerebral malaria at the University College Hospital, Ibadan, Nigeria. Of the 50 children studied, 43 (68%) made a full recovery, 5 (105) developed neurological sequelae while 11(22%) died. Biochemical derangements observed among the children included azotaemia (29%), elevated plasma creatinine (20%), metabolic acidiosis (22%) and hyponatraemia (16%). Metabolic acidosis and elevated plasma creatinine on admission were significantly associated with a poor outcome (p |
| Document Type: |
article in journal/newspaper |
| File Description: |
application/pdf |
| Language: |
English |
| Relation: |
http://ajol.info/index.php/wajm/article/view/27996 |
| Availability: |
http://ajol.info/index.php/wajm/article/view/27996 |
| Accession Number: |
edsbas.5D309B37 |
| Database: |
BASE |