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Technical review by the ESPGHAN Special Interest Group on Gut Microbiota and Modifications on the health outcomes of infant formula supplemented with prebiotics

Title: Technical review by the ESPGHAN Special Interest Group on Gut Microbiota and Modifications on the health outcomes of infant formula supplemented with prebiotics
Authors: Mihatsch, Walter; Dinleyici, Ener Cagri; Canani, Roberto Berni; Hojsak, Iva; Mosca, Alexis; Orel, Rok; Salvatore, Silvia; Savino, Francesco; Szajewska, Hania; van den Akker, Chris H. P.; Weizman, Zvi; Vandenplas, Yvan; null, null
Contributors: Mihatsch, Walter; Dinleyici, Ener Cagri; Canani, Roberto Berni; Hojsak, Iva; Mosca, Alexi; Orel, Rok; Salvatore, Silvia; Savino, Francesco; Szajewska, Hania; Van Den Akker, Chris H. P.; Weizman, Zvi; Vandenplas, Yvan; Null, Null
Publication Year: 2026
Collection: IRIS Università degli Studi di Napoli Federico II
Subject Terms: breast feeding; formula feeding; fructo‐oligosaccharide; galactooligosaccharide; infant feeding; microbiome
Description: Prebiotics are defined as substrates that are selectively utilized by host microorganisms, conferring health benefits. This technical review focusing on prebiotic-supplemented infant formulas is one of the five manuscripts developed by the European Society for Pediatric Gastroenterology, Hepatology, and Nutrition Special Interest Group on Gut Microbiota and Modifications (SIG-GMM). The SIG-GMM conducted a technical review to evaluate the clinical outcomes of prebiotic-supplemented infant formulas in healthy infants (0-12 months) that were published before 2024. The review focused on the following clinical outcomes: anthropometric measurements, stool frequency and consistency, gastrointestinal symptoms, allergy prevention, infection prevention, and safety/tolerability. Following the review, all 20 SIG members anonymously voted on each statement, scoring them from 0 to 9. A score ≥6 indicated agreement with a statement. A statement was rejected if ≥75% of the members voted
Document Type: article in journal/newspaper
Language: English
Relation: info:eu-repo/semantics/altIdentifier/wos/WOS:001490435200001; volume:82; issue:1; firstpage:252; lastpage:277; numberofpages:26; journal:JOURNAL OF PEDIATRIC GASTROENTEROLOGY AND NUTRITION; https://hdl.handle.net/11588/1023256
DOI: 10.1002/jpn3.70064
Availability: https://hdl.handle.net/11588/1023256; https://doi.org/10.1002/jpn3.70064; https://onlinelibrary.wiley.com/doi/epdf/10.1002/jpn3.70064
Rights: info:eu-repo/semantics/openAccess ; license:Dominio pubblico ; license uri:http://creativecommons.org/publicdomain/zero/1.0/
Accession Number: edsbas.5D4EB62F
Database: BASE