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Blood pressure-lowering effects of nifedipine/candesartan combinations in high-risk individuals: Subgroup analysis of the DISTINCT randomised trial

Title: Blood pressure-lowering effects of nifedipine/candesartan combinations in high-risk individuals: Subgroup analysis of the DISTINCT randomised trial
Authors: Mancia, G; Cha, G; Gil-Extremera, B; Harvey, P; Lewin, AJ; Villa, G; Kjeldsen, SE; Agaiby, J; Aggarwal, N; Ainsworth, P; Akhras, R; Amaluan, V; Ballarin, A; Bardauskiene, L; Berra, FC; Blagden, M; Bodalia, B; Borghi, C; Bundy, C; Burgess, L; Buynak, R; Cafferata, A; Cahill, T; Capiau, L; Capuano, V; Casanova, R; Cecil, J; Chapman, J; Chilvers, M; Christensen, S; Cho, Y-H; Chung, W-B; Cipollone, F; Coca, A; Colombo, H; Contreras, EM; Crowley, D; Cusco-Prieto, B; Decarlini, F; Doh, J-H; Dzongowski, P; Dzyak, G; Ellery, A; Extremera, BG; Farias, E; Farrington, C; Fidelholtz, J; Fouche, L; Gabito, A; Gainza, M; Gani, M; Gaunt, R; Gelersztein, E; Giuliano, M; Glazunov, A; Glorioso, N; Goloschekin, B; Gumbley, M; Gupta, A; Guzman, L; Ha, J-W; Hart, R; Haworth, D; Henein, S; Henry, D; Her, S-H; Heyvaert, F; Hollanders, G; Hominal, M; Hong, B-K; Hong, T-J; Hwang, K-K; Jacovides, A; Jacqmein, J; Jeon, HK; Jones, N; Kanani, S; Kang, H; Karpenko, O; Kenton, D; Kimzey, N; Kovalenko, V; Kushnir, M; Lasko, B; Lee, KJ; Lee, N; Lewin, A; Litvak, M; Luksiene, D; Majul, C; Mannarino, E; Manuale, O; Marcadis, A; Miller, D; Mills, R; Misik, K; Mortelmans, J; O'Mahony, M; O'Mahony, W; Park, C; Pedrinelli, R; Petrulioniene, Z; Pettyjohn, F; Piskorz, D; Poss, G; Pudi, K; Pyun, WB; Raad, G; Raila, G; Ramirez Espinosa, MF; Ramlachan, P; Rhee, M; Rudenko, L; Ruiz, TS; Ryan, J; Schacter, G; Shin, J-H; Short, D; Sica, D; Sirenko, Y; Slapikas, R; Somani, R; Stanislavchuk, M; Stewart, R; Svishchenko, Y; Sychov, O; Teitelbaum, I; Tseluyko, V; Van Rensburg, DJ; Vaquer Perez, JV; Via, LM; Vico, M; Vizir, V; Vogel, D; Wellmann, H; Yoo, BS
Contributors: Mancia, G; Cha, G; Gil-Extremera, B; Harvey, P; Lewin, A; Villa, G; Kjeldsen, S; Agaiby, J; Aggarwal, N; Ainsworth, P; Akhras, R; Amaluan, V; Ballarin, A; Bardauskiene, L; Berra, F; Blagden, M; Bodalia, B; Borghi, C; Bundy, C; Burgess, L; Buynak, R; Cafferata, A; Cahill, T; Capiau, L; Capuano, V; Casanova, R; Cecil, J; Chapman, J; Chilvers, M; Christensen, S; Cho, Y; Chung, W; Cipollone, F; Coca, A; Colombo, H; Contreras, E; Crowley, D; Cusco-Prieto, B; Decarlini, F; Doh, J; Dzongowski, P; Dzyak, G; Ellery, A; Extremera, B; Farias, E; Farrington, C; Fidelholtz, J; Fouche, L; Gabito, A; Gainza, M; Gani, M; Gaunt, R; Gelersztein, E; Giuliano, M; Glazunov, A; Glorioso, N; Goloschekin, B; Gumbley, M; Gupta, A; Guzman, L; Ha, J; Hart, R; Haworth, D; Henein, S; Henry, D; Her, S; Heyvaert, F; Hollanders, G; Hominal, M; Hong, B; Hong, T; Hwang, K; Jacovides, A; Jacqmein, J; Jeon, H; Jones, N; Kanani, S; Kang, H; Karpenko, O; Kenton, D; Kimzey, N; Kovalenko, V; Kushnir, M; Lasko, B; Lee, K; Lee, N; Litvak, M; Luksiene, D; Majul, C; Mannarino, E; Manuale, O; Marcadis, A; Miller, D; Mills, R; Misik, K; Mortelmans, J
Publisher Information: Nature Publishing Group
Publication Year: 2017
Collection: Università degli Studi di Milano-Bicocca: BOA (Bicocca Open Archive)
Subject Terms: Antihypertensive Agent; Benzimidazole; Blood Pressure; Calcium Channel Blocker; Drug Therapy; Combination; Female; Human; Hypertension; Male; Middle Aged; Nifedipine; Tetrazole; Internal Medicine
Description: The DISTINCT study (reDefining Intervention with Studies Testing Innovative Nifedipine GITS - Candesartan Therapy) investigated the efficacy and safety of nifedipine GITS/candesartan cilexetil combinations vs respective monotherapies and placebo in patients with hypertension. This descriptive sub-analysis examined blood pressure (BP)-lowering effects in high-risk participants, including those with renal impairment (estimated glomerular filtration rate
Document Type: article in journal/newspaper
Language: English
Relation: info:eu-repo/semantics/altIdentifier/pmid/27511476; info:eu-repo/semantics/altIdentifier/wos/WOS:000394137500004; volume:31; issue:3; firstpage:178; lastpage:188; numberofpages:11; journal:JOURNAL OF HUMAN HYPERTENSION; https://hdl.handle.net/10281/199995
DOI: 10.1038/jhh.2016.54
Availability: https://hdl.handle.net/10281/199995; https://doi.org/10.1038/jhh.2016.54
Rights: info:eu-repo/semantics/openAccess ; license:Creative Commons ; license uri:http://creativecommons.org/licenses/by-nc-nd/4.0/
Accession Number: edsbas.5DE718E8
Database: BASE