| Title: |
Increased complement activation is a distinctive feature of severe SARS-CoV-2 infection |
| Authors: |
Ma, Lina; Sahu, Sanjaya K.; Cano, Marlene; Kuppuswamy, Vasanthan; Bajwa, Jamal; McPhatter, Ja’Nia; Pine, Alexander; Meizlish, Matthew L.; Goshua, George; Chang, C. Hong; Zhang, Hanming; Price, Christina; Bahel, Parveen; Rinder, Henry; Lei, Tingting; Day, Aaron; Reynolds, Daniel; Wu, Xiaobo; Schriefer, Rebecca; Rauseo, Adriana M.; Goss, Charles W.; O’Halloran, Jane A.; Presti, Rachel M.; Kim, Alfred H.; Gelman, Andrew E.; Dela Cruz, Charles S.; Lee, Alfred I.; Mudd, Philip A.; Chun, Hyung J.; Atkinson, John P.; Kulkarni, Hrishikesh S. |
| Contributors: |
National Heart, Lung, and Blood Institute; National Eye Institute; National Institute of General Medical Sciences; National Institute of Allergy and Infectious Diseases; National Institute of Arthritis and Musculoskeletal and Skin Diseases; Robert E. Leet and Clara Guthrie Patterson Trust; American Heart Association; Emergency Medicine Foundation; Foundation for Barnes-Jewish Hospital; Institute of Clinical and Translational Sciences; Children’s Discovery Institute |
| Source: |
Science Immunology ; volume 6, issue 59 ; ISSN 2470-9468 |
| Publisher Information: |
American Association for the Advancement of Science (AAAS) |
| Publication Year: |
2021 |
| Description: |
Increased complement activation is observed in COVID-19 compared with non-COVID respiratory illness and is a key marker of organ failure. |
| Document Type: |
article in journal/newspaper |
| Language: |
English |
| DOI: |
10.1126/sciimmunol.abh2259 |
| Availability: |
https://doi.org/10.1126/sciimmunol.abh2259; https://syndication.highwire.org/content/doi/10.1126/sciimmunol.abh2259; https://www.science.org/doi/pdf/10.1126/sciimmunol.abh2259 |
| Rights: |
https://creativecommons.org/licenses/by/4.0/ |
| Accession Number: |
edsbas.5E4D7972 |
| Database: |
BASE |