| Title: |
Multiple insecticide resistance in Aedes aegypti (Diptera: Culicidae) populations compromises the effectiveness of dengue vector control in French Guiana. |
| Authors: |
Dusfour, Isabelle; Thalmensy, Véronique; Gaborit, Pascal; Issaly, Jean; Carinci, Romuald; Girod, Romain |
| Contributors: |
Institut Pasteur de la Guyane; Pasteur Network (Réseau International des Instituts Pasteur); Financial support: French ministry of health (department of health and social development, Division of health and environment); Acknowledgments To the vector control service team of Cayenne, French Guiana, for performing the spatial sprays, particularly to Dr Patrick Rabarison, Mr Léon Lescot, Mr Herman Pagamin and Mr Jean-Paul Alexander. |
| Source: |
ISSN: 0074-0276. |
| Publisher Information: |
CCSD; Instituto Oswaldo Cruz, Ministério da Saúde |
| Publication Year: |
2011 |
| Collection: |
Réseau International des Instituts Pasteur, Paris: HAL-RIIP |
| Subject Terms: |
Aedes aegypti; insecticide resistance; vector control; French Guiana; MESH: Aedes*/enzymology; MESH: Animals; MESH: Organophosphates; MESH: Pyrethrins; MESH: Dengue/prevention & control; MESH: Female; MESH: French Guiana; MESH: Insecticide Resistance; MESH: Insecticides; MESH: Lethal Dose 50; MESH: Mosquito Control; [SDV.BA]Life Sciences [q-bio]/Animal biology |
| Description: |
International audience ; In French Guiana, pyrethroids and organophosphates have been used for many years against Aedes aegypti. We aimed to establish both the resistance level of Ae. aegypti and the ultra low volume spray efficacy to provide mosquito control services with practical information to implement vector control and resistance management. Resistance to deltamethrin and fenitrothion was observed. In addition, the profound loss of efficacy of AquaK'othrine® and the moderate loss of efficacy of Paluthion® 500 were recorded. Fenitrothion remained the most effective candidate for spatial application in French Guiana until its removal in December 2010. Further investigation of the mechanism of resistance to deltamethrin demonstrated the involvement of mixed-function oxidases and, to a lesser extent, of carboxylesterases. However, these observations alone cannot explain the level of insecticide resistance we observed during tube and cage tests. |
| Document Type: |
article in journal/newspaper |
| Language: |
English |
| Relation: |
info:eu-repo/semantics/altIdentifier/pmid/21655824; PUBMED: 21655824 |
| DOI: |
10.1590/S0074-02762011000300015 |
| Availability: |
https://riip.hal.science/pasteur-00638832; https://riip.hal.science/pasteur-00638832v1/document; https://riip.hal.science/pasteur-00638832v1/file/Multiple_insecticide_resistance_in_aedes_aegypti_populations_compromises.pdf; https://doi.org/10.1590/S0074-02762011000300015 |
| Rights: |
http://creativecommons.org/licenses/by-nc/ ; info:eu-repo/semantics/OpenAccess |
| Accession Number: |
edsbas.5EBAFD4E |
| Database: |
BASE |