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The construct validity of real-world digital mobility outcomes in people with chronic obstructive pulmonary disease

Title: The construct validity of real-world digital mobility outcomes in people with chronic obstructive pulmonary disease
Authors: Megaritis, D.; Long, M.; de las Heras, M.; Alcaraz-Serrano, V.; Alvarez, P.; Becker, C.; Braun, J.; Buekers, J.; Buttery, S.; Caulfield, B.; Cereatti, A.; Chynkiamis, N.; Del Din, S.; Delgado-Ortiz, L.; Demeyer, H.; Frei, A.; Gimeno-Santos, E.; Hopkinson, N.S.; Ionescu, A.; Jansen, C.-P.; Josa-Culleré, A.; Kirsten, A.; Koch, S.; Lemos, J.; Philip, K.E.J.; Rochester, L.; Sharrack, B.; Singleton, D.; Vereijken, B.; Vogiatzis, I.; Watz, H.; Lanfranchi, V.; Troosters, T.; Garcia-Aymerich, J.
Publisher Information: European Respiratory Society (ERS)
Publication Year: 2026
Collection: White Rose Research Online (Universities of Leeds, Sheffield & York)
Description: Background Recent advances in wearable technologies make it possible to accurately quantify real-world mobility performance through technically validated digital mobility outcomes (DMOs). Aim To evaluate the construct validity (convergent, divergent, and known-groups validity) of 24 DMOs quantifying walking activity (amount and pattern) and gait (pace, rhythm, and bout-to-bout variability) in people with chronic obstructive pulmonary disease (COPD). Methods Part of the Mobilise-D observational cohort study, people with COPD, recruited from seven European sites, wore an activity monitor for seven days during daily life. Functional capacity, health status, dyspnoea, lung function, quadriceps torque, and experience of difficulty with physical activity were used as constructs for convergent validity testing (Pearson/Spearman correlation coefficients). Diastolic blood pressure was used as an unrelated construct for divergent validity (criterion: |r|
Document Type: article in journal/newspaper
File Description: text
Language: English
ISSN: 2312-0541
Relation: https://eprints.whiterose.ac.uk/id/eprint/238905/1/ERJ%20Open%20Res-2026-Megaritis-23120541.00993-2025.pdf; Megaritis, D. orcid.org/0000-0001-6786-4346 , Long, M. orcid.org/0000-0001-5943-3415 , de las Heras, M. et al. (31 more authors) (2026) The construct validity of real-world digital mobility outcomes in people with chronic obstructive pulmonary disease. ERJ Open Research. ISSN: 2312-0541
Availability: https://eprints.whiterose.ac.uk/id/eprint/238905/
Rights: cc_by_nc_4
Accession Number: edsbas.5F597D7D
Database: BASE