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Study of antimicrobial prescribing pattern in a tertiary care teaching hospital at Dehradun, Uttarakhand, India - A tool to teach clinical pharmacology to MBBS students

Title: Study of antimicrobial prescribing pattern in a tertiary care teaching hospital at Dehradun, Uttarakhand, India - A tool to teach clinical pharmacology to MBBS students
Authors: Beg, Mirza Atif; Bawa, Shalu; Dutta, Shaktibala; Anjoom, Mohammad; Vishal, Subhash
Source: International Journal of Basic & Clinical Pharmacology; Vol. 5 No. 6 (2016): November-December 2016; 2444-2448 ; 2279-0780 ; 2319-2003
Publisher Information: Medip Academy
Publication Year: 2016
Subject Terms: Antimicrobials; Prescribing pattern; WHO drug use indicators; Rational prescription
Description: Background: Due to increasing resistance to a majority of antimicrobials, it becomes very necessary to teach undergraduate students, the future prescribers, about the judicious and rational use of antimicrobial drugs. The objective of this study was to impart the basic clinical skills to undergraduate MBBS students which will form an integral component of practising rational therapeutics.Methods: A total no of 737 cases were followed up by the 5th semester 2nd Professional MBBS students in the Department of Pharmacology at Shri Guru Ram Rai Institute of Medical and Health Sciences (SGRRIM and HS), Dehradun from June 2013 to July 2015. Patients were analysed on various WHO drug use indicators like drug formulations, drugs prescribed per prescription, Fixed dose Combinations (FDCs), drugs prescribed from National List of Essential Medicines (NLEM) and drugs prescribed by generic names.Results: A total of 737 prescriptions were analysed. Male: Female ratio was 1.74:1 (63.50%:36.50%). Majority of the patients 218 (29.58%) were in 16-30 years age group. A total of 1205 antimicrobials were prescribed. 304 (25.23%) cephalosporins were most frequent followed by 184(15.27%) penicillins, 176(14.61%) antitubercular drugs, 163(13.53%) nitroimidazoles, 143 (11.87%) fluoroquinolones, 102 (8.46%) aminoglycosides, 29 (2.41%) macrolides, 19 (1.58%) tetracyclines, 12 (1%) carbapenems, 11 (0.91%) antimalarials, 11 (0.91%) antihelminthics, 6 (0.50%) glycopeptides, 4 (0.33%) lincosamides and 41 (3.41%) miscellaneous antimicrobials. Most frequently prescribed antimicrobial was Ceftriaxone which was given in 97 (8.05 %) patients. A total of 424 (35.19%) oral antimicrobials, 777 (64.48%) injectable antimicrobials and 04 (0.33%) local/topical antimicrobial drugs were prescribed. 5.13 drugs per prescription and 1.64 antimicrobials per prescription were prescribed. 2100 (55.56%) drugs were prescribed from National List of Essential Medicine 2015 (NLEM 2015). 1177 (97.68%) antimicrobials were prescribed from NLEM. 1110 (92.12%) ...
Document Type: article in journal/newspaper
File Description: application/pdf
Language: English
Relation: https://www.ijbcp.com/index.php/ijbcp/article/view/30/28; https://www.ijbcp.com/index.php/ijbcp/article/view/30
DOI: 10.18203/2319-2003.ijbcp20164102
Availability: https://www.ijbcp.com/index.php/ijbcp/article/view/30; https://doi.org/10.18203/2319-2003.ijbcp20164102
Rights: Copyright (c) 2016 International Journal of Basic & Clinical Pharmacology
Accession Number: edsbas.5FF41BAD
Database: BASE