| Title: |
Trends in the prevalence of hepatitis B infection among women giving birth in New South Wales |
| Authors: |
Deng, L; Reekie, J; Ward, JS; Hayen, A; Kaldor, JM; Kong, M; Hunt, JM; Liu, B |
| Source: |
urn:ISSN:0025-729X ; urn:ISSN:1326-5377 ; Medical Journal of Australia, 206, 7, 301-305 |
| Publisher Information: |
Wiley |
| Publication Year: |
2017 |
| Collection: |
UNSW Sydney (The University of New South Wales): UNSWorks |
| Subject Terms: |
3215 Reproductive Medicine; 32 Biomedical and Clinical Sciences; 42 Health Sciences; Hepatitis; Pediatric Research Initiative; Infectious Diseases; Digestive Diseases; Liver Disease; Hepatitis - B; Reproductive health and childbirth; Infection; 3 Good Health and Well Being; Adult; Child; Female; Hepatitis B; Hepatitis B virus; Humans; Immunization Programs; Infant; Newborn; Logistic Models; Mass Vaccination; New South Wales; Odds Ratio; Parity; Population Groups; Pregnancy; Pregnancy Complications; Infectious |
| Description: |
Objectives: To evaluate the effect of targeted and catch-up hepatitis B virus (HBV) vaccination programs in New South Wales on HBV prevalence among women giving birth for the first time. Design: Observational study linking data from the NSW Perinatal Data Collection for women giving birth during 2000e2012 with HBV notifications in the NSW Notifiable Conditions Information Management System. Main outcome measures: HBV prevalence in Indigenous Australian, non-Indigenous Australian-born, and overseas-born women giving birth. Results: Of 482 944 women who gave birth to their first child, 3383 (0.70%) were linked to an HBV notification. HBV prevalence was 1.95% (95% CI, 1.88e2.02%) among overseas born women, 0.79% (95% CI, 0.63e0.95%) among Indigenous Australian women, and 0.11% (95% CI, 0.09e0.12%) among non-Indigenous Australian-born women. In Indigenous Australian women, prevalence was significantly lower for those who had been eligible for inclusion in the targeted at-risk newborn or universal school-based vaccination programs (maternal year of birth, 1992e1999: 0.15%) than for those who were not (born ≤ 1981: 1.31%; for trend, P < 0.001). There was no statistically significant downward trend among non-Indigenous Australian-born or overseas-born women. HBV prevalence was higher among Indigenous women residing in regional and remote areas than those in major cities (adjusted odds ratio [aOR], 2.23; 95% CI, 1.40e3.57), but lower for non-Indigenous (aOR, 0.39; 95% CI, 0.28e0.55) and overseas-born women (aOR, 0.61; 95% CI, 0.49e0.77). Conclusion: Among women giving birth, there was a significant reduction in HBV prevalence in Indigenous women associated with the introduction of the HBV vaccination program in NSW, although prevalence remains higher than among non-Indigenous Australian-born women, and it also varies by region of residence. Continuing evaluation is needed to ensure that the prevalence of HBV infections continues to fall in Australia. |
| Document Type: |
article in journal/newspaper |
| Language: |
unknown |
| Relation: |
http://purl.org/au-research/grants/nhmrc/APP1108115; https://hdl.handle.net/1959.4/unsworks_45619; https://doi.org/10.5694/mja16.00823 |
| DOI: |
10.5694/mja16.00823 |
| Availability: |
https://hdl.handle.net/1959.4/unsworks_45619; https://doi.org/10.5694/mja16.00823 |
| Rights: |
metadata only access ; http://purl.org/coar/access_right/c_14cb ; CC-BY-NC-ND ; https://creativecommons.org/licenses/by-nc-nd/4.0/ |
| Accession Number: |
edsbas.609CCCB9 |
| Database: |
BASE |