| Title: |
Comparison of children and adults undergoing subdural grid electrode implantation or stereoelectroencephalography in a refractory epilepsy cohort from four European centers |
| Authors: |
Rados, Matea; Beerepoot, Shanice; Tisdall,Martin M; Pressler,Ronit M; Cross,J Helen; Thornton,Rachel C; Diehl,Beate; McEvoy,Andrew W; Miserocchi,Anna; Sander,Josemir W; Duncan,John S; de Tisi,Jane; Cardinale,Francesco; Tassi,Laura; Russo,Giorgio Lo; Francione,Stefano; Lamberink, Herm J; Leijten, Frans S S; Otte, Willem M; van der Salm, Sandra M A; Braun, Kees P J; van Eijsden, Pieter; MS Oogheelkunde; Brain; CTI Nierkens; Diagnostiek & Vroege Psychose Medisch; Neurologen; Projectafdeling KIND; Cancer; Neurochirurgen |
| Publication Year: |
2025 |
| Subject Terms: |
epilepsy surgery; invasive electroencephalography; SEEG; Neurology; Clinical Neurology; Journal Article |
| Description: |
Objective: Children with refractory focal epilepsy differ from adults, although many centers will offer invasive electroencephalography (iEEG) to both. Outcomes in terms of likelihood of resection and subsequent seizure outcome after either subdural grid electrode implantation (SDE) or stereoelectroencephalography (SEEG) have, however, not been directly compared between age groups. Methods: We retrospectively included adults and children undergoing iEEG monitoring at four European centers. We compared the two age groups and techniques regarding complication rate, chance of proceeding to resection, and seizure freedom. Results: In total, 857 individuals were included (447 SEEG, 410 SDE; 572 adults, 285 children). Adults more often had a history of focal to bilateral tonic–clonic seizures (FBTCS) and prior epilepsy surgery and were more often magnetic resonance imaging-negative. Children had a higher seizure frequency and rate of preexisting neurologic deficits. In SEEG, likelihood of resection was 64% in adults and 76% in children (p |
| Document Type: |
article in journal/newspaper |
| File Description: |
application/pdf |
| Language: |
English |
| ISSN: |
0013-9580 |
| Relation: |
https://dspace.library.uu.nl/handle/1874/466216 |
| Availability: |
https://dspace.library.uu.nl/handle/1874/466216 |
| Rights: |
info:eu-repo/semantics/OpenAccess |
| Accession Number: |
edsbas.609E8604 |
| Database: |
BASE |