| Title: |
HHIPL1, a Gene at the 14q32 Coronary Artery Disease Locus, Positively Regulates Hedgehog Signaling and Promotes Atherosclerosis |
| Authors: |
Aravani, Dimitra; Morris, Gavin E; Jones, Peter D; Tattersall, Helena K; Karamanavi, Elisavet; Kaiser, Michael A; Kostogrys, Renata B; Ghaderi Najafabadi, Maryam; Andrews, Sarah L; Nath, Mintu; Ye, Shu; Stringer, Emma J; Samani, Nilesh J; Webb, Tom R |
| Contributors: |
University of Aberdeen.Other Applied Health Sciences; University of Aberdeen.Medical Statistics |
| Publication Year: |
2019 |
| Collection: |
Aberdeen University Research Archive (AURA) |
| Subject Terms: |
SDG 3 - Good Health and Well-being; atherosclerosis; coronary artery disease; genome-wide association study; hedgehogs; signaling; MIGRATION; ACTIVATION; VESSEL; PROTEIN; ANGIOGENESIS; SONIC HEDGEHOG; MUSCLE-CELL PROLIFERATION; INDUCTION; PATHWAY; EXPRESSION; R Medicine; Cardiology and Cardiovascular Medicine; Physiology (medical); British Heart Foundation; SP/18/8/33620; SP/16/4/32697 |
| Description: |
The research leading to these results has received funding from the European Union Seventh Framework Programme FP7/2007–2013 under grant agreement number HEALTH-F2-2013–601456, a Transatlantic Networks of Excellence Award (12CVD02) from The Leducq Foundation and the British Heart Foundation (SP/18/8/33620) as a partner of the European Research Area Network on Cardiovascular Diseases (ERA-CVD) druggable-MI-genes (01KL1802) and supported by the UK National Institute for Health Research (NIHR) Leicester Biomedical Research Centre. Dr Samani is a UK NIHR Senior Investigator. Drs Morris, Ye, and Webb are funded by the British Heart Foundation (SP/16/4/32697). ; Peer reviewed |
| Document Type: |
article in journal/newspaper |
| File Description: |
application/pdf |
| Language: |
English |
| Relation: |
Circulation; 145528258; 000478747900014; 85071063221; Aravani , D , Morris , G E , Jones , P D , Tattersall , H K , Karamanavi , E , Kaiser , M A , Kostogrys , R B , Ghaderi Najafabadi , M , Andrews , S L , Nath , M , Ye , S , Stringer , E J , Samani , N J & Webb , T R 2019 , ' HHIPL1 , a Gene at the 14q32 Coronary Artery Disease Locus, Positively Regulates Hedgehog Signaling and Promotes Atherosclerosis ' , Circulation , vol. 140 , no. 6 , pp. 500–513 . https://doi.org/10.1161/CIRCULATIONAHA.119.041059; http://hdl.handle.net/2164/12682; http://www.scopus.com/inward/record.url?scp=85071063221&partnerID=8YFLogxK; 140 |
| DOI: |
10.1161/CIRCULATIONAHA.119.041059 |
| DOI: |
10.1161/circulationaha.119.041059 |
| Availability: |
http://hdl.handle.net/2164/12682; https://doi.org/10.1161/CIRCULATIONAHA.119.041059; http://www.mendeley.com/research/hhipl1-gene-14q32-coronary-artery-disease-locus-positively-regulates-hedgehog-signaling-promotes-ath; http://www.scopus.com/inward/record.url?scp=85071063221&partnerID=8YFLogxK; https://www.ahajournals.org/doi/suppl/10.1161/circulationaha.119.041059 |
| Accession Number: |
edsbas.614726FC |
| Database: |
BASE |