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Improving the Differential Diagnosis of Otitis Media With Effusion Using Wideband Acoustic Immittance

Title: Improving the Differential Diagnosis of Otitis Media With Effusion Using Wideband Acoustic Immittance
Authors: Merchant, Gabrielle R.; Al-Salim, Sarah; Tempero, Richard M.; Fitzpatrick, Denis; Neely, Stephen T.
Source: Ear & Hearing ; volume 42, issue 5, page 1183-1194 ; ISSN 1538-4667
Publisher Information: Ovid Technologies (Wolters Kluwer Health)
Publication Year: 2021
Description: Objectives: The objective of this work is to determine whether there is a systematic effect of middle ear effusion volume on wideband acoustic immittance in children with surgically confirmed otitis media with effusion. Design: Wideband acoustic immittance was measured in 49 ears from children (9 months to 11 years) who had a diagnosis of otitis media with effusion and compared to 14 ears from children (10 months to 10 years) without a recent history of otitis media. For children with otitis media with effusion, wideband acoustic immittance testing took place in the child’s preoperative waiting room before surgical placement of tympanostomy tubes. Testing was completed in a pressurized condition (wideband tympanometry) for all ears as well as in an ambient condition in a subset of ears. Intraoperative findings regarding effusion volume were reported by the surgeons immediately before tube placement and confirmed following myringotomy. This classified the volume of effusion as compared to middle ear volume categorically as either full, partial, or clear of effusion. The type of wideband acoustic immittance explored in this work was absorbance. Absorbance responses were grouped based on effusion volume into one of four groups: full effusions, partial effusions, ears clear of effusion at the time of surgery, and normal control ears. Standard tympanometry was also completed on all ears. Results: Absorbance is systematically reduced as the volume of the middle ear effusion increases. This reduction is present at most frequencies but is greatest in the frequency range from 1 to 5 kHz. A multivariate logistic regression approach was utilized to classify ears based on effusion volume. The regression approach classified ears as effusion present (full and partial ears) or absent (clear ears and normal control ears) with 100% accuracy, ears with effusion present as either partial or full with 100% accuracy, and ears without effusion as either normal control ears or ears clear of effusion with 75% accuracy. Regression ...
Document Type: article in journal/newspaper
Language: English
DOI: 10.1097/aud.0000000000001037
DOI: 10.1097/AUD.0000000000001037
Availability: https://doi.org/10.1097/aud.0000000000001037; https://journals.lww.com/10.1097/AUD.0000000000001037
Accession Number: edsbas.61AB8943
Database: BASE