| Title: |
Lifting the veil of secrecy: maternal and neonatal outcome of oocyte donation pregnancies in Germany |
| Authors: |
Altmann, Judith; Kummer, J.; Herse, F.; Hellmeyer, L.; Schlembach, D.; Henrich, W.; Weichert, A. |
| Source: |
http://lobid.org/resources/99370671687406441#!, 306(1):59-69. |
| Publication Year: |
2021 |
| Collection: |
Publisso (ZB MED-Publikationsportal Lebenswissenschaften) |
| Subject Terms: |
Female [MeSH]; Preeclampsia; Confidentiality [MeSH]; Humans [MeSH]; Oocyte-donation; Retrospective Studies [MeSH]; Pregnancy Outcome/epidemiology [MeSH]; Egg-donation; Fertilization in Vitro/adverse effects [MeSH]; Peripartum hemorrhage; Pre-Eclampsia/epidemiology [MeSH]; Maternal-Fetal Medicine; Oocyte Donation/adverse effects [MeSH]; Pre-Eclampsia/etiology [MeSH]; Cesarean Section/adverse effects [MeSH]; Pregnancy [MeSH]; Pregnancy risks |
| Description: |
Background!#!In Germany, performing fertility procedures involving oocyte donation is illegal, as stated by the Embryo Protection Law. Nonetheless, in our clinical routine we attend to a steadily rising number of pregnant women, who have sought oocyte donation abroad. Due to the legal circumstances many women opt to keep the origin of their pregnancy a secret. However, studies have shown, that oocyte donation is an independent risk factor for the development of pregnancy complications, such as preeclampsia.!##!Objective!#!The aim of this study is to evaluate maternal and neonatal outcomes of oocyte donation pregnancies in three large obstetric care units in Berlin, Germany.!##!Methods!#!We retrospectively analyzed all available medical data on oocyte donation pregnancies at Charité University hospital, Vivantes Hospital Friedrichshain, and Neukoelln in the German capital.!##!Results!#!We included 115 oocyte donation (OD) pregnancies in the present study. Our data are based on 62 singleton, 44 twin, 7 triplet, and 2 quadruplet oocyte donation pregnancies. According to our data, oocyte donation pregnancies are associated with a high risk of adverse maternal and fetal outcome, i.e., hypertension in pregnancy, preterm delivery, Cesarean section as mode of delivery, and increased peripartum hemorrhage.!##!Conclusion!#!Although oocyte donation is prohibited by German law, many couples go abroad to seek reproductive measures using oocyte donation after former treatment options have failed. OD pregnancies are associated with a high risk of preeclampsia, C-section as mode of delivery, and peripartum hemorrhage. Detailed knowledge of the associated risks is of utmost importance to both the patient and the treating physician and midwife. |
| Document Type: |
article in journal/newspaper |
| Language: |
English |
| Relation: |
https://repository.publisso.de/resource/frl:6450518; https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9300520/ |
| DOI: |
10.1007/s00404-021-06264-8 |
| Availability: |
https://repository.publisso.de/resource/frl:6450518; https://doi.org/10.1007/s00404-021-06264-8; https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9300520/ |
| Rights: |
https://creativecommons.org/licenses/by/4.0/ |
| Accession Number: |
edsbas.622A1109 |
| Database: |
BASE |