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ASSOCIATIONS OF INTER-ARM BLOOD PRESSURE DIFFERENCE WITH TREATMENT RESPONSE IN NEWLY TREATED HYPERTENSION

Title: ASSOCIATIONS OF INTER-ARM BLOOD PRESSURE DIFFERENCE WITH TREATMENT RESPONSE IN NEWLY TREATED HYPERTENSION
Authors: Clark, Chris; Jordan, Andrew; Anning, Christine; Wilkes, Lindsay; Ball, Claire; Pamphilon, Nicola; Bellenger, Nicholas; Shore, Angela; Sharp, Andrew
Source: Journal of Hypertension ; volume 41, issue Suppl 3, page e152 ; ISSN 0263-6352 1473-5598
Publisher Information: Ovid Technologies (Wolters Kluwer Health)
Publication Year: 2023
Description: Objective: Inter-arm differences (IAD) in systolic blood pressure (SBP) predict future cardiovascular mortality and morbidity. IAD varies between measures and gets smaller with repeated measures. The relationship of IAD to response to antihypertensive treatment is unknown. We set out to examine associations of IAD with BP treatment response over 18 weeks in treatment-naïve adults with moderate to severe hypertension. Design and method: We previously reported that nurse-led accelerated stepwise management of treatment-naïve grade II/III hypertension is feasible, safe and effective, achieving control of SBP to < 140 mmHg for 76% after 18 weeks. Using this cohort, univariable associations of IAD (mean of 8 simultaneous BP measurements) with vascular and clinical indices, and with BP change on treatment, were examined with mixed-effects linear regression models. Candidate univariable indices (p
Document Type: article in journal/newspaper
Language: English
DOI: 10.1097/01.hjh.0000940380.38422.a4
Availability: https://doi.org/10.1097/01.hjh.0000940380.38422.a4; https://journals.lww.com/10.1097/01.hjh.0000940380.38422.a4
Accession Number: edsbas.62A95C05
Database: BASE