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Antibiotic prescriptions for oral diseases in India: evidence from national prescription data

Title: Antibiotic prescriptions for oral diseases in India: evidence from national prescription data
Authors: Mathur, MR; Nagrath, D; Mishra, VK; Harris, R; Saeed, SS; Selvaraj, S; Mehta, A; Farooqui, HH
Publisher Information: BMC
Publication Year: 2023
Collection: Queen Mary University of London: Queen Mary Research Online (QMRO)
Subject Terms: Antimicrobial Resistance; India; Dental Ailments; Prescription Rates
Description: Introduction The key objective of this research was to describe the prescription rate of various antibiotics for dental problems in India and to study the relevance of the prescriptions by analysing antibiotic types associated with different dental diagnoses, using a large-scale nationally representative dataset. Methods We used a 12-month period (May 2015 to April 2016) medical audit dataset from IQVIA (formerly IMS Health). We coded the dental diagnosis provided in the medical audit data to the International Statistical Classification of Diseases and Related Health Problems (ICD-11) and the prescribed antibiotics for the diagnosis to the Anatomic Therapeutic Chemical (ATC) -2020 classification of the World Health Organization. The primary outcome measure was the medicine prescription rate per 1,000 persons per year (PRPY1000). Results Our main findings were—403 prescriptions per 1,000 persons per year in the year 2015 -2016 for all dental ailments. Across all ATC level 1 classification, ‘Diseases of hard tissues’ made up the majority of the prescriptions. ‘Beta-lactam’, ‘Penicillin,’ and ‘Cephalosporins’ were the most commonly prescribed antibiotics for dental diagnoses followed by ‘Macrolides’ and ‘Quinolones’. ‘Dental caries’, ‘Discoloration of tooth’, and ‘Toothache’ were the most common reasons for ‘Beta-Lactams’ and ‘Penicillin’ prescriptions. Conclusion To conclude our study reports first ever country (India) level estimates of antibiotic prescription by antibiotic classes, age groups, and ICD-11 classification for dental ailments.
Document Type: article in journal/newspaper
Language: English
Relation: BMC Oral Health; ARTN 170; https://qmro.qmul.ac.uk/xmlui/handle/123456789/93027
DOI: 10.1186/s12903-023-02889-0
Availability: https://qmro.qmul.ac.uk/xmlui/handle/123456789/93027; https://doi.org/10.1186/s12903-023-02889-0
Rights: This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativeco mmons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data. ; © The Author(s) 2023.
Accession Number: edsbas.62CB311
Database: BASE