| Title: |
Therapeutically relevant engraftment of a CRISPR-Cas9–edited HSC-enriched population with HbF reactivation in nonhuman primates |
| Authors: |
Humbert, Olivier; Radtke, Stefan; Samuelson, Clare; Carrillo, Ray R.; Perez, Anai M.; Reddy, Sowmya S.; Lux, Christopher; Pattabhi, Sowmya; Schefter, Lauren E.; Negre, Olivier; Lee, Ciaran M.; Bao, Gang; Adair, Jennifer E.; Peterson, Christopher W.; Rawlings, David J.; Scharenberg, Andrew M.; Kiem, Hans-Peter |
| Contributors: |
National Heart, Lung, and Blood Institute; Cancer Prevention and Research Institute of Texas |
| Source: |
Science Translational Medicine ; volume 11, issue 503 ; ISSN 1946-6234 1946-6242 |
| Publisher Information: |
American Association for the Advancement of Science (AAAS) |
| Publication Year: |
2019 |
| Description: |
CRISPR-Cas9–edited hematopoietic stem cells produce long-term engraftment and fetal hemoglobin reactivation in nonhuman primates. |
| Document Type: |
article in journal/newspaper |
| Language: |
English |
| DOI: |
10.1126/scitranslmed.aaw3768 |
| Availability: |
https://doi.org/10.1126/scitranslmed.aaw3768; https://syndication.highwire.org/content/doi/10.1126/scitranslmed.aaw3768; https://www.science.org/doi/pdf/10.1126/scitranslmed.aaw3768 |
| Accession Number: |
edsbas.62EA4550 |
| Database: |
BASE |