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Outcomes of Patients Hospitalized with Community-Acquired, Health Care-Associated, and Hospital-Acquired Pneumonia

Title: Outcomes of Patients Hospitalized with Community-Acquired, Health Care-Associated, and Hospital-Acquired Pneumonia
Authors: Venditti, M; Falcone, M; Corrao,S; Licata, G; Serra, P; Study Group of the Italian Society of Internal Medicine; Salerno, F; Filetti, S; D’Erasmo, E; Rossi Fanelli, F; Cricco, L; Gasbarrone, L; Serafini, C; Ghio, R; Zoppoli, G; Cortellaro, M; Magenta, M; Nuti, R; Valenti, R; Milano, V; Brandimarte, C; Carfagna, P; Di Sciacca, R; Tuttolomondo, A; Serra, MG; Bernardi, M; Li Bassi, S; Stanghellini, V; Boschi, E; Antonaci, S; Vella, F; Catalano, A; Zeneroli, ML; Ascari, E; Veggetti, A; Manfredini, R; Gamberoni, S; Guarnieri, G; Fioretto, A; Di Michele, D; Parisi, D; Liberato, NL; Ronchi, E; Sturbini, S; Canafoglia, P; Gallerani, M; Boari, B; Nielsen, I; Rossetti, A; Bernasconi, M; Giannatempo, C; Turconi, R; Colombo, M; Cappelli; R. Guidi; V; Tassara, R; De Melis, D; Cosentini, R; Arioli, M; Gobbo, G; Presotto, F; Gallana, S; Balduini, C; Bertolino, G; Fera, G; Corazza, RG; Capriglione, I; Pilerio, G; Cappellini, MD; Fabio, G; Carrabba, M; Wu, SC; Secchi, MB; Leone, M; De Feudis, L; Gunelli, M; Ferri, O; Doroldi, C; Pistis, R; Sabbadini, MG; Tresoldi, M; Tedeschi, A; Rossio, R; Lambelet, P; Fascetti, S; Vanoli, M; Casella, G; Agabiti Rosei, E; Salvi, A; Noto, A; Perciaccante, A; Santini, C; Galie`, M; Gasbarrini, G; Grieco, A; Nardi, B; Baritussio, AG; Vannuccini, R; Cappelletti, M; Gentiloni Silveri, N; Lechi, A; Montesi, G.; ANNONI, GIORGIO
Contributors: Venditti, M; Falcone, M; Corrao, S; Licata, G; Serra, P; Study Group of the Italian Society of Internal, M; Salerno, F; Filetti, S; D’Erasmo, E; Rossi Fanelli, F; Cricco, L; Gasbarrone, L; Serafini, C; Ghio, R; Zoppoli, G; Cortellaro, M; Magenta, M; Nuti, R; Valenti, R; Milano, V; Brandimarte, C; Carfagna, P; Di Sciacca, R; Tuttolomondo, A; Serra, M; Bernardi, M; Li Bassi, S; Stanghellini, V; Boschi, E; Antonaci, S; Vella, F; Catalano, A; Zeneroli, M; Ascari, E; Veggetti, A; Manfredini, R; Gamberoni, S; Guarnieri, G; Fioretto, A; Di Michele, D; Parisi, D; Liberato, N; Ronchi, E; Sturbini, S; Canafoglia, P; Gallerani, M; Boari, B; Nielsen, I; Annoni, G; Rossetti, A; Bernasconi, M; Giannatempo, C; Turconi, R; Colombo, M; Cappelli; R., G; V; Tassara, R; De Melis, D; Cosentini, R; Arioli, M; Gobbo, G; Presotto, F; Gallana, S; Balduini, C; Bertolino, G; Fera, G; Corazza, R; Capriglione, I; Pilerio, G; Cappellini, M; Fabio, G; Carrabba, M; Wu, S; Secchi, M; Leone, M; De Feudis, L; Gunelli, M; Ferri, O; Doroldi, C; Pistis, R; Sabbadini, M; Tresoldi, M; Tedeschi, A; Rossio, R; Lambelet, P; Fascetti, S; Vanoli, M; Casella, G; Agabiti Rosei, E; Salvi, A; Noto, A; Perciaccante, A; Santini, C; Galie`, M; Gasbarrini, G; Grieco, A; Nardi, B; Baritussio, A
Publisher Information: American College of Physicians]
Publication Year: 2009
Collection: Università degli Studi di Milano-Bicocca: BOA (Bicocca Open Archive)
Subject Terms: Acquired Pneumonia; Patients outcomes; Settore MEDS-05/A - Medicina interna
Description: Background: Traditionally, pneumonia has been classified as either community- or hospital-acquired. Although only limited data are available, health care–associated pneumonia has been recently proposed as a new category of respiratory infection. “Health care–associated pneumonia” refers to pneumonia in patients who have recently been hospitalized, had hemodialysis, or received intravenous chemotherapy or reside in a nursing home or long-term care facility. Objective: To ascertain the epidemiology and outcome of community-acquired, health care–associated, and hospital-acquired pneumonia in adults hospitalized in internal medicine wards. Design: Multicenter, prospective observational study. Setting: 55 hospitals in Italy comprising 1941 beds. Patients: 362 patients hospitalized with pneumonia during two 1-week surveillance periods. Measurements: Cases of radiologically and clinically assessed pneumonia were classified as community-acquired, health care–associated, or hospital-acquired and rates were compared. Results: Of the 362 patients, 61.6% had community-acquired pneumonia, 24.9% had health care–associated pneumonia, and 13.5% had hospital-acquired pneumonia. Patients with health care–associated pneumonia had higher mean Sequential Organ Failure Assessment scores than did those with community-acquired pneumonia (3.0 vs. 2.0), were more frequently malnourished (11.1% vs. 4.5%, and had more frequent bilateral (34.4% vs. 19.7%) and multilobar (27.8% vs. 21.5%) involvement on a chest radiograph. Patients with health care–associated pneumonia also had higher fatality rates (17.8% [CI, 10.6% to 24.9%] vs. 6.7% [CI, 2.9% to 10.5%]) and longer mean hospital stay (18.7 days [CI, 15.9 to 21.5 days] vs. 14.7 days [CI, 13.4 to 15.9 days]). Logistic regression analysis revealed that depression of consciousness (odds ratio [OR], 3.2 [CI, 1.06 to 9.8]), leukopenia (OR, 6.2 [CI, 1.01 to 37.6]), and receipt of empirical antibiotic therapy not recommended by international guidelines (OR, 6.4 [CI, 2.3 to 17.6]) were ...
Document Type: article in journal/newspaper
Language: English
Relation: info:eu-repo/semantics/altIdentifier/pmid/19124816; info:eu-repo/semantics/altIdentifier/wos/WOS:000262655100003; volume:150; issue:1; firstpage:19; lastpage:26; numberofpages:8; journal:ANNALS OF INTERNAL MEDICINE; https://hdl.handle.net/10281/9059
Availability: https://hdl.handle.net/10281/9059
Rights: info:eu-repo/semantics/openAccess
Accession Number: edsbas.65470EE6
Database: BASE