| Title: |
Long-term cardiometabolic health in people born after assisted reproductive technology: a multi-cohort analysis |
| Authors: |
Elhakeem, A; Taylor, AE; Inskip, HM; Huang, JY; Mansell, T; Rodrigues, C; Asta, F; Blaauwendraad, SM; Haberg, SE; Halliday, J; Harskamp-van Ginkel, MW; He, JR; Jaddoe, VWV; Lewis, S; Maher, GM; Manios, Y; McCarthy, FP; Reiss, IKM; Rusconi, F; Salika, T; Tafflet, M; Qiu, X; Asvold, BO; Burgner, D; Chan, JKY; Gagliardi, L; Gaillard, R; Heude, B; Magnus, MC; Moschonis, G; Murray, D; Nelson, SM; Porta, D; Saffery, R; Barros, H; Eriksson, JG; Vrijkotte, TGM; Lawlor, DA |
| Contributors: |
Instituto de Saúde Pública da Universidade do Porto |
| Publisher Information: |
oxford University Press |
| Publication Year: |
2023 |
| Collection: |
Repositório Aberto da Universidade do Porto |
| Subject Terms: |
Blood pressure; Glucose; In vitro fertilization; Lipids; Meta-analysis; Pooled longitudinal trajectory analysis |
| Description: |
Aims To examine associations of assisted reproductive technology (ART) conception (vs. natural conception: NC) with offspring cardiometabolic health outcomes and whether these differ with age. Methods and results Differences in systolic (SBP) and diastolic blood pressure (DBP), heart rate (HR), lipids, and hyperglycaemic/insulin resistance markers were examined using multiple linear regression models in 14 population-based birth cohorts in Europe, Australia, and Singapore, and results were combined using meta-analysis. Change in cardiometabolic outcomes from 2 to 26 years was examined using trajectory modelling of four cohorts with repeated measures. 35 938 (654 ART) offspring were included in the meta-analysis. Mean age ranged from 13 months to 27.4 years but was |
| Document Type: |
article in journal/newspaper |
| File Description: |
application/pdf |
| Language: |
English |
| Relation: |
Eur Heart J. 2023 Apr 21;44(16):1464-1473. doi:10.1093/eurheartj/ehac726.; https://academic.oup.com/eurheartj/article/44/16/1464/7026325; https://hdl.handle.net/10216/154288 |
| DOI: |
10.1093/eurheartj/ehac726 |
| Availability: |
https://hdl.handle.net/10216/154288; https://doi.org/10.1093/eurheartj/ehac726 |
| Rights: |
info:eu-repo/semantics/openAccess |
| Accession Number: |
edsbas.65D99EFC |
| Database: |
BASE |