| Title: |
Prostatic diseases in transgender women: a systematic review of diagnosis, risk, and management |
| Authors: |
Bourillon, Alice; Guillot-Tantay, Cyrille; Freton, Lucas; Zhao, Lee; Mesnard, Benoît; Morel-Journel, Nicolas; Mathieu, Romain; Neuville, Paul; Schirmann, Aurélie; Peyronnet, Benoît; Madec, François Xavier |
| Contributors: |
Université de Rennes (UR); Hôpital Foch Suresnes; New York University Langone Medical Center (NYU Langone Medical Center); NYU System (NYU); Centre Hospitalier Universitaire de Nantes = Nantes University Hospital (CHU Nantes); Hospices Civils de Lyon (HCL); Handicap neuromusculaire : Physiopathologie, Biothérapie et Pharmacologies appliquées (END-ICAP); Université de Versailles Saint-Quentin-en-Yvelines (UVSQ)-Institut National de la Santé et de la Recherche Médicale (INSERM); none |
| Source: |
ISSN: 2689-5269 ; International Journal of Transgender Health ; https://hal.science/hal-05106059 ; International Journal of Transgender Health, 2025, pp.1-13. ⟨10.1080/26895269.2025.2503225⟩. |
| Publisher Information: |
CCSD; Taylor and Francis Group |
| Publication Year: |
2025 |
| Collection: |
Université de Versailles Saint-Quentin-en-Yvelines: HAL-UVSQ |
| Subject Terms: |
Prostate; Transgender women; Prostatic Neoplasms; Transgenderism; Lower urinary tract symptoms; [SDV]Life Sciences [q-bio] |
| Description: |
International audience ; Introduction: Most transgender women have their prostate left in situ throughout and after their transition. Managing prostate-related conditions in transgender women remains challenging due to the lack of clear recommendations. This review aims to summarize the available data on prostate health, including cancer screening and treatment, lower urinary tract symptoms, and prostate evaluation.Material and methodsA comprehensive literature review was conducted in accordance with the PRISMA statement using PubMed, Embase, and The Cochrane Library, with the keywords (prostate), (lower urinary tract symptoms (LUTS)), (prostate evaluation), and (transgender women). All relevant data were analyzed.ResultsTwenty studies were included in the final analysis: 15 focused on prostate cancer, four on LUTS, and one on prostate evaluation. A total of 961 prostate cancer cases were identified. Of the 17 detailed oncologic treatments, the most common were surgery and hormone therapy. Data regarding LUTS and prostate evaluation were very limited; the most frequently reported symptom was a split urinary stream. Surgical interventions for LUTS included two cases of transurethral resection of the prostate (TURP) and one Rezum procedure. Prostate evaluation was performed via transvaginal exam in 50 patients. Transvaginal ultrasonographic assessment of the prostate was feasible in 67 out of 70 patients (96%).ConclusionThe present systematic review demonstrates that prostatic diseases can occur in transgender women. Neovaginal prostatic exam appears as the appropriate way to assess the prostate on physical exam. The paucity of data highlights the need to raise awareness of healthcare professionals and to promote further research on this critical issue. |
| Document Type: |
article in journal/newspaper |
| Language: |
English |
| DOI: |
10.1080/26895269.2025.2503225 |
| Availability: |
https://hal.science/hal-05106059; https://hal.science/hal-05106059v1/document; https://hal.science/hal-05106059v1/file/Bourillon%20-%202025%20-%20Prostatic%20diseases%20in%20transgender%20women%20a%20systematic%20review%20of%20diagnosis,%20risk,%20and%20management%20_%20manuscript-r1.pdf; https://doi.org/10.1080/26895269.2025.2503225 |
| Rights: |
https://creativecommons.org/licenses/by-nc/4.0/ ; info:eu-repo/semantics/OpenAccess |
| Accession Number: |
edsbas.65F5CD5 |
| Database: |
BASE |