| Title: |
Pathogenic lower genital tract organisms in HIV-infected and uninfected women, and their association with postpartum infectious morbidity |
| Authors: |
Sebitloane, H M; Moodley, J; Esterhuizen, T M |
| Source: |
South African Medical Journal; Vol 101, No 7 (2011); 466-469 ; 2078-5135 ; 0256-9574 |
| Publisher Information: |
South African Medical Association |
| Publication Year: |
2011 |
| Collection: |
South African Medical Journal (SAMJ) |
| Subject Terms: |
medicine; women's health; HIV infection; pregnancy |
| Subject Geographic: |
South Africa; female |
| Description: |
Objectives. To determine the prevalence of vaginal pathogens during pregnancy and their impact on postpartum infectious morbidity among antiretroviral-naïve HIV-infected, and HIV-uninfected, women. Methods. Vaginal swabs were obtained during early labour by speculum examination prior to digital vaginal examination, and sent for microscopy and culture. Women were assessed for infectious complications within 24 - 72 hours of delivery, and up to 2 weeks postpartum. Results. Laboratory results were available for 801 women who delivered vaginally (418 HIV infected and 383 uninfected). The baseline characteristics of the two groups were comparable, and the median CD4 count for HIV-infected women (N=391) was 416/µl. Fifty-five per cent (54.8%) of women had positive cultures (439/801), more among those who were HIV infected, than uninfected (60% v. 49.1%, p=0.002). Women with positive cultures had slightly higher rates of infectious morbidity than those without (20.5% v. 15.2%, p=0.052). Trichomonas vaginalis and group B streptococcus were significantly associated with sepsis (p=0.023 and |
| Document Type: |
article in journal/newspaper |
| File Description: |
application/pdf |
| Language: |
English |
| Relation: |
http://samj.org.za/index.php/samj/article/view/4449/3274; http://samj.org.za/index.php/samj/article/downloadSuppFile/4449/1665; http://samj.org.za/index.php/samj/article/view/4449 |
| DOI: |
10.7196/SAMJ.4449 |
| Availability: |
http://samj.org.za/index.php/samj/article/view/4449; https://doi.org/10.7196/SAMJ.4449 |
| Rights: |
Copyright of published material remains in the Authors’ name. This allows authors to use their work for their own non-commercial purposes without seeking permission from the Publisher, subject to properly acknowledging the Journal as the original place of publication. Authors are free to copy, print and distribute their articles, in full or in part, for teaching activities, and to deposit or include their work in their own personal or institutional database or on-line website. Authors are requested to inform the Journal/Publishers of their desire/intention to include their work in a thesis or dissertation or to republish their work in any derivative form (but not for commercial use).  Material submitted for publication in the SAMJ is accepted provided it has not been published or submitted for publication elsewhere. Please inform the editorial team if the main findings of your paper have been presented at a conference and published in abstract form, to avoid copyright infringement. |
| Accession Number: |
edsbas.676A6243 |
| Database: |
BASE |