Cardiovascular disease, chronic kidney disease, and diabetes mortality burden of cardiometabolic risk factors from 1980 to 2010: a comparative risk assessment
| Title: | Cardiovascular disease, chronic kidney disease, and diabetes mortality burden of cardiometabolic risk factors from 1980 to 2010: a comparative risk assessment |
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| Authors: | Danaei G; Lu Y; Singh GM; Stevens GA; Cowan MJ; Farzadfar F; Lin JK; Finucane MM; Rao M; Khang Y. H; Riley LM; Mozaffarian D; Lim SS; Ezzati M; Aamodt G; Abdeen Z; Abdella NA; Abdul Rahim HF; Addo J; Aekplakorn W; Afi fi MM; Agabiti Rosei E; Aguilar Salinas CA; Agyemang C; Ali MK; Ali MM; Al Nsour M; Al Nuaim AR; Ambady R; Di Angelantonio E; Aro P; Azizi F; Babu BV; Bahalim AN; BARBAGALLO, Carlo Maria; Barbieri MA; Barcelo A; Barreto SM; Barros H; Bautista LE; Benetos A; Bjerregaard P; Bjorkelund C; Bo S; Bobak M; Bonora E; Botana MA; Bovet P; Breckenkamp J; Breteler MM; Broda G; Brown IJ; Bursztyn M; Cabrera de Leon A; Campos H; Cappuccio FP; Capuano V; Casiglia E; Castellano M; Castetbon K; Cea L; Chang C. J; Chaouki N; Chatterji S; Chen C. J; Chen Z; Choi J. S; Chua L; Cifkova R; Cobiac LJ; Cooper RS; Corsi AM; Costanza MC; Craig CL; Dankner RS; Dastgiri S; Delgado E; Dinc G; Doi Y; Dong G. H; Dorsi E; Dragano N; Drewnowski A; Eggertsen R; Elliott P; Anders Engeland; Erem C; Esteghamati A; Fall CHD; Fan J. G; Ferreccio C; Fezeu L; Firmo JO; Florez HF; Fornes NF; Fowkes FGR; Franceschini G; Frisk F; Fuchs FD; Fuller EL; Getz L; Giampaoli S; Gomez LF; Gomez Zumaquero JM; Graff –Iversen S; Grant JF; Guerrero Carvajal R; Gulliford MC; Gupta R; Gupta PC; Gureje O; Gutierrez HR; Hansen TW; Hata J; He J; Heim N; Heinrich J; Hemmingsson T; Hennis A; Herman WH; Herrera VM; Ho S; Holdsworth M; Hollman Frisman G; Hopman WM; Hussain A; Husseini A; Ibrahim MM; Ikeda N; Jacobsen BK; Jaddou HY; Jafar TH; Janghorbani M; Jasienska G; Joffres MR; Jonas JB; Kadiki OA; Kalter Leibovici O; Kamadjeu RM; Kaptoge S; Karalis I; Kastarinen MJ; Katz J; Keinan Boker L; Kelly P; Khalilzadeh O; Kiechl S; Woong Kim KW; Kiyohara Y; Kobayashi J; Krause MP; Kubinova R; Kurjata P; Kusuma YS; Lam TH; Langhammer A; Lawes CMM; Le C; Lee J; Levy Marchal C; Lewington S; Li Y; Lim TO; Lin X; Lin C. C; Lin H. H; Lind L; Lissner L; Liu X; Lopez Jaramillo P; Lorbeer R; Ma G; Ma S; Macia F; MacLean DR; Maggi S; Magliano DJ; Makdisse M; Mancia G; Mannami T; Marques Vidal P; Mbanya JCN; McFarlane Anderson N; Miccoli R; Miettola J; Minh HV; Miquel JF; J. Miranda JJ; Mohamed MK; Mohan V; Mohanna S; Mokdad A; Mollentze WF; Morales DD; Morgan K; Muiesan LM; Muntoni S; Nabipour I; Nakagami T; Nangia V; Nemesure B; Neovius M; Nerhus KA; Nervi F; Neuhauser H; Nguyen M; Ninomiya T; Noale M; Oh SW; Ohkubo T; Olivieri O; Onal AE; Onat A; Orostegui M; Ouedraogo H; Pan W. A; Panagiotakos DB; Panza F; Park Y; Passos VMA; Pednekar MS; Pelizzari PM; Peres MA; Perez C; Perez Fernandez R; Pichardo R; Hwee Pin Phua; Francesco Pistelli; Plans P; Polakowska M; Poulter N; Prabhakaran D; Qiao Q; Rafiei M; Raitakari OT; Ramos LR; Rampal S; Rampal L; Rasmussen F; Reddy KKR; Josep Redon J; Revilla L; Reyes GarciaV; Roaeid RB; Robinson CA; Rodriguez Artalejo F; Rojas Martinez R; Ronkainen K; Rosero Bixby L; Roth GA; Sachdev HS; Sanchez JR; Sanisoglu SY; Sans S; Sarraf Zadegan N; Scazufca M; Schaan BD; Schapochnik N; Schelleman H; Schneider IJC; Schooling CM; Schwarz B; Sekuri C; Sereday MS; Serra Majem L; Shaw J; Shera AS; Shi Z; Shiri R; Shu XO; Santos Silva DA; Silva E; Simons LA; Smith M; Soderberg S; Soebardi S; Solfrizzi V; Sonestedt E; Soysal A; StattinP; Stein AD; Stergiou GS; Stessman J; Sudo A; Suka M; Sundh V; Sundquist K; Sundstrom J; Swai AB; Tai ES; Tambs K; Tesfaye F; Thomas GN; Thorogood M; Tilvis RS; Tobias M; Torheim LE; Trenkwalder P; Tuomilehto JO; Tur JA; Tzourio C; Uhernik A; Ukoli FA; Unwin N; Vander Hoorn S; Vanderpump MP; Varo JJ; Veierod MB; Velasquez Melendez G; Verschuren M; Viet L; Villalpando S; Vioque J; Vollenweider P; Volpato S; Wang N; Wang YX; Ward M; Waspadji S; Welin LX; Whitlock G; Wilhelmsen L; Willeit J; Woodward M; Wormser D; Xavier AJ; Xu F; Xu L; Yamamoto A; Yang G; Yang X; Yeh L. C; Yoon J. S; You Q; Yu Z; Zhang J; Zhang L; Zheng W; Zhou M. |
| Contributors: | Danaei G; Lu Y; Singh GM; Stevens GA; Cowan MJ; Farzadfar F; Lin JK; Finucane MM; Rao M; Khang Y-H; Riley LM; Mozaffarian D; Lim SS; Ezzati M; Aamodt G; Abdeen Z; Abdella NA; Abdul Rahim HF; Addo J; Aekplakorn W; Afi fi MM; Agabiti-Rosei E; Aguilar Salinas CA; Agyemang C; Ali MK; Ali MM; Al-Nsour M; Al-Nuaim AR; Ambady R; Di Angelantonio E; Aro P; Azizi F; Babu BV; Bahalim AN; Barbagallo CM; Barbieri MA; Barcelo A; Barreto SM; Barros H; Bautista LE; Benetos A; Bjerregaard P; Bjorkelund C; Bo S; Bobak M; Bonora E; Botana MA; Bovet P; Breckenkamp J; Breteler MM; Broda G; Brown IJ; Bursztyn M; Cabrera de Leon A; Campos H; Cappuccio FP; Capuano V; Casiglia E; Castellano M; Castetbon K; Cea L; Chang C-J; Chaouki N; Chatterji S; Chen C-J; Chen Z; Choi J-S; Chua L; Cifkova R; Cobiac LJ; Cooper RS; Corsi AM; Costanza MC; Craig CL; Dankner RS; Dastgiri S; Delgado E; Dinc G; Doi Y; Dong G-H; Dorsi E; Dragano N; Drewnowski A; Eggertsen R; Elliott P; Anders Engeland; Erem C; Esteghamati A; Fall CHD; Fan J-G; Ferreccio C; Fezeu L; Firmo JO; Florez HF; Fornes NF; Fowkes FGR; Franceschini G; Frisk F; Fuchs FD; Fuller EL |
| Publisher Information: | Lancet |
| Publication Year: | 2014 |
| Collection: | IRIS Università degli Studi di Palermo |
| Subject Terms: | Cardiovascular disease,Diabetes Mellitus; chronic kidney disease; Settore MED/09 - Medicina Interna |
| Description: | Background High blood pressure, blood glucose, serum cholesterol, and BMI are risk factors for cardiovascular diseases and some of these factors also increase the risk of chronic kidney disease and diabetes. We estimated mortality from cardiovascular diseases, chronic kidney disease, and diabetes that was attributable to these four cardiometabolic risk factors for all countries and regions from 1980 to 2010. Methods We used data for exposure to risk factors by country, age group, and sex from pooled analyses of populationbased health surveys. We obtained relative risks for the eff ects of risk factors on cause-specifi c mortality from metaanalyses of large prospective studies. We calculated the population attributable fractions for- each risk factor alone, and for the combination of all risk factors, accounting for multicausality and for mediation of the eff ects of BMI by the other three risks. We calculated attributable deaths by multiplying the cause-specifi c population attributable fractions by the number of disease-specifi c deaths. We obtained cause-specifi c mortality from the Global Burden of Diseases, Injuries, and Risk Factors 2010 Study. We propagated the uncertainties of all the inputs to the fi nal estimates. Findings In 2010, high blood pressure was the leading risk factor for deaths due to cardiovascular diseases, chronic kidney disease, and diabetes in every region, causing more than 40% of worldwide deaths from these diseases; high BMI and glucose were each responsible for about 15% of deaths, and high cholesterol for more than 10%. After accounting for multicausality, 63% (10·8 million deaths, 95% CI 10·1–11·5) of deaths from these diseases in 2010 were attributable to the combined eff ect of these four metabolic risk factors, compared with 67% (7·1 million deaths, 6·6–7·6) in 1980. The mortality burden of high BMI and glucose nearly doubled from 1980 to 2010. At the country level, age-standardised death rates from these diseases attributable to the combined eff ects of these four risk factors ... |
| Document Type: | article in journal/newspaper |
| Language: | English |
| Relation: | info:eu-repo/semantics/altIdentifier/wos/WOS:000341799900023; volume:2; issue:8; firstpage:634; lastpage:647; numberofpages:14; journal:THE LANCET DIABETES & ENDOCRINOLOGY; https://hdl.handle.net/10447/98961 |
| DOI: | 10.1016/S2213-8587(14)70102-0 |
| Availability: | https://hdl.handle.net/10447/98961; https://doi.org/10.1016/S2213-8587(14)70102-0 |
| Rights: | info:eu-repo/semantics/openAccess |
| Accession Number: | edsbas.67859339 |
| Database: | BASE |