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Integrated microbiome sequencing data analysis with nf-core

Title: Integrated microbiome sequencing data analysis with nf-core
Authors: Fellows Yates, James; Stallforth, Pierre; Warinner, Christina; nf-core
Publisher Information: Zenodo
Publication Year: 2024
Collection: Zenodo
Subject Terms: bioinformatics; nextflow; microbiome; NFDI; nf-core; pipelines; workflows
Description: Metagenomics, a common sequencing method used in microbiome research, refers totechniques that aim to simultaneously analyse the DNA from all organisms in a sample. Giventhe ever-growing size of microbiome sequencing datasets needed to address ecologicalquestions, and the need to compare against a large number of genomes, Nextflow is an idealframework for building scalable and computationally efficient pipelines. One reason for thecurrent popularity of Nextflow within bioinformatics is the nf-core initiative, which aims to buildcommunity-based, software-development best-practices and (bio)informatic pipelines written inthe workflow manager language Nextflow. This poster will introduce the nf-core offerings of community-developed pipelines formetagenomics. Of these, I will highlight on pipelines for metagenomic taxonomic profiling(nf-core/taxprofiler), metagenomic de novo assembly (nf-core/mag), and screening forantimicrobial resistance and natural product genes (nf-core/funcscan). I will also show howthese pipelines fit in the wider nf-core ecosystem, and how they can be utilised together forscientists in microbial ecology, microbiome research, and even ancient DNA.
Document Type: text
Language: English
Relation: https://zenodo.org/records/14242373; oai:zenodo.org:14242373; https://doi.org/10.5281/zenodo.14242373
DOI: 10.5281/zenodo.14242373
Availability: https://doi.org/10.5281/zenodo.14242373; https://zenodo.org/records/14242373
Rights: Creative Commons Attribution 4.0 International ; cc-by-4.0 ; https://creativecommons.org/licenses/by/4.0/legalcode
Accession Number: edsbas.67DC1D23
Database: BASE