| Title: |
A novel, multidomain, primary care nurse-led and mHealth-assisted intervention for dementia risk reduction in middle-aged adults (HAPPI MIND): study protocol for a cluster randomised controlled trial |
| Authors: |
Cross, AJ; Geethadevi, GM; Magin, P; Baker, AL; Bonevski, B; Godbee, K; Ward, SA; Mahal, A; Versace, V; Bell, JS; Namara, KM; O'Reilly, SL; Thomas, D; Manias, E; Anstey, KJ; Varnfield, M; Jayasena, R; Elliott, RA; Lee, CY; Walker, C; van den Bosch, D; Tullipan, M; Ferreira, C; George, J |
| Source: |
urn:ISSN:2044-6055 ; BMJ Open, 13, 12, e073709 |
| Publisher Information: |
BMJ |
| Publication Year: |
2023 |
| Collection: |
UNSW Sydney (The University of New South Wales): UNSWorks |
| Subject Terms: |
4203 Health Services and Systems; 4205 Nursing; 42 Health Sciences; Acquired Cognitive Impairment; Brain Disorders; Neurosciences; Alzheimer's Disease including Alzheimer's Disease Related Dementias (AD/ADRD); Health Services; Minority Health; Aging; Prevention; Health Disparities and Racial or Ethnic Minority Health Research; Primary Health Care; Dementia; Health Disparities; Clinical Trials and Supportive Activities; Clinical Research; Behavioral and Social Science; Neurodegenerative; Alzheimer's Disease; 3.1 Primary prevention interventions to modify behaviours or promote wellbeing; 7.3 Management and decision making; Neurological; 3 Good Health and Well Being; 4 Quality Education; Humans; Middle Aged; Primary Care Nursing; Quality of Life; Randomized Controlled Trials as Topic |
| Description: |
Introduction Middle-aged multidomain risk reduction interventions targeting modifiable risk factors for dementia may delay or prevent a third of dementia cases in later life. We describe the protocol of a cluster randomised controlled trial (cRCT), HAPPI MIND (Holistic Approach in Primary care for PreventIng Memory Impairment aNd Dementia). HAPPI MIND will evaluate the efficacy of a multidomain, nurse-led, mHealth supported intervention for assessing dementia risk and reducing associated risk factors in middle-aged adults in the Australian primary care setting. Methods and analysis General practice clinics (n≥26) across Victoria and New South Wales, Australia, will be recruited and randomised. Practice nurses will be trained to implement the HAPPI MIND intervention or a brief intervention. Patients of participating practices aged 45–65 years with ≥2 potential dementia risk factors will be identified and recruited (approximately 15 patients/clinic). Brief intervention participants receive a personalised report outlining their risk factors for dementia based on Australian National University Alzheimer’s Disease Risk Index (ANU-ADRI) scores, education booklet and referral to their general practitioner as appropriate. HAPPI MIND participants receive the brief intervention as well as six individualised dementia risk reduction sessions with a nurse trained in motivational interviewing and principles of behaviour change, a personalised risk reduction action plan and access to the purpose-built HAPPI MIND smartphone app for risk factor self-management. Follow-up data collection will occur at 12, 24 and 36 months. Primary outcome is ANU-ADRI score change at 12 months from baseline. Secondary outcomes include change in cognition, quality of life and individual risk factors of dementia. |
| Document Type: |
article in journal/newspaper |
| File Description: |
application/pdf |
| Language: |
unknown |
| Relation: |
https://hdl.handle.net/1959.4/unsworks_85727 |
| DOI: |
10.1136/bmjopen-2023-073709 |
| Availability: |
https://hdl.handle.net/1959.4/unsworks_85727; https://unsworks.unsw.edu.au/bitstreams/bfc6da20-9c24-4fd4-a5ac-de9e2fbff312/download; https://doi.org/10.1136/bmjopen-2023-073709 |
| Rights: |
open access ; https://purl.org/coar/access_right/c_abf2 ; CC BY-NC ; https://creativecommons.org/licenses/by-nc/4.0/ ; free_to_read |
| Accession Number: |
edsbas.683B354B |
| Database: |
BASE |