Original Contribution Is 2,3,5-Pyrroletricarboxylic Acid in Hair a Better Risk Indicator for Melanoma than Traditional Epidemiologic Measures for Skin Phenotype?
| Title: | Original Contribution Is 2,3,5-Pyrroletricarboxylic Acid in Hair a Better Risk Indicator for Melanoma than Traditional Epidemiologic Measures for Skin Phenotype? |
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| Authors: | Stefano Rosso; Roberto Zanetti; Maria Jose ́ Sánchez; Ana Mir; Dora Loria; Anne Østerlind; Maria-dolores Chirlaque; Cesare Barbera; Carmela Lauria; Daniela Balzi; Marina Zoccola |
| Contributors: | The Pennsylvania State University CiteSeerX Archives |
| Source: | http://aje.oxfordjournals.org/content/165/10/1170.full.pdf. |
| Publication Year: | 2006 |
| Collection: | CiteSeerX |
| Description: | This study aims to assess type of melanin as a risk indicator for skin tumors, in a sample of melanoma cases and controls within a larger multicenter study (Helios 2), held in Europe and South America in 2001–2002. In each case and control, the melanin content in hair was assessed by three methods: 1) the amount of 2,3,5-pyrroletricarboxylic acid (PTCA); 2) the absorbance ratio with ultraviolet spectroscopy; and 3) the spectra of near-infrared spectroscopy. Statistical analysis was performed in a Bayesian setting, defining priors for con-founders and effect modifiers from the larger study data set. Subjects with values of PTCA of less than 85 ng/mg |
| Document Type: | text |
| File Description: | application/pdf |
| Language: | English |
| Relation: | http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.586.6097; http://aje.oxfordjournals.org/content/165/10/1170.full.pdf |
| Availability: | http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.586.6097; http://aje.oxfordjournals.org/content/165/10/1170.full.pdf |
| Rights: | Metadata may be used without restrictions as long as the oai identifier remains attached to it. |
| Accession Number: | edsbas.68DF3ACE |
| Database: | BASE |