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Two-Year Outcomes of a Population-Based Intervention for Preschool Language Delay: An RCT

Title: Two-Year Outcomes of a Population-Based Intervention for Preschool Language Delay: An RCT
Authors: Wake, Melissa; Levickis, Penny; Tobin, Sherryn; Gold, Lisa; Ukoumunne, Obioha C; Goldfeld, Sharon; Zens, Naomi; Le, Ha ND; Law, James; Reilly, Sheena
Publisher Information: American Academy of Pediatrics
Publication Year: 2015
Collection: Griffith University: Griffith Research Online
Subject Terms: Biomedical and clinical sciences; Reproductive medicine not elsewhere classified; Psychology
Description: OBJECTIVE: We have previously shown short-term benefits to phonology, letter knowledge, and possibly expressive language from systematically ascertaining language delay at age 4 years followed by the Language for Learning intervention. Here, we report the trial’s definitive 6-year outcomes. METHODS: Randomized trial nested in a population-based ascertainment. Children with language scores >1.25 SD below the mean at age 4 were randomized, with intervention children receiving 18 1-hour home-based therapy sessions. Primary outcome was receptive/expressive language. Secondary outcomes were phonological, receptive vocabulary, literacy, and narrative skills; parent-reported pragmatic language, behavior, and health-related quality of life; costs of intervention; and health service use. For intention-to-treat analyses, trial arms were compared using linear regression models. RESULTS: Of 1464 children assessed at age 4, 266 were eligible and 200 randomized; 90% and 82% of intervention and control children were retained respectively. By age 6, mean language scores had normalized, but there was little evidence of a treatment effect for receptive (adjusted mean difference 2.3; 95% confidence interval [CI] –1.2 to 5.7; P = .20) or expressive (0.8; 95% CI –1.6 to 3.2; P = .49) language. Of the secondary outcomes, only phonological awareness skills (effect size 0.36; 95% CI 0.08–0.65; P = .01) showed benefit. Costs were higher for intervention families (mean difference AU$4276; 95% CI: $3424 to $5128). CONCLUSIONS: Population-based intervention targeting 4-year-old language delay was feasible but did not have lasting impacts on language, possibly reflecting resolution in both groups. Long-term literacy benefits remain possible but must be weighed against its cost. ; No Full Text
Document Type: article in journal/newspaper
Language: English
Relation: Pediatrics; https://hdl.handle.net/10072/125303
DOI: 10.1542/peds.2015-1337
Availability: https://hdl.handle.net/10072/125303; https://doi.org/10.1542/peds.2015-1337
Accession Number: edsbas.692B7438
Database: BASE