| Title: |
Perceptual Learning as a Rehabilitation Approach to Enhance Motion Processing in Maculopathy Patients |
| Authors: |
Michaud, Célia; Faurite, Cynthia; Guénot, Jade; Gallice, Mathilde; Chiquet, Christophe; Vayssière, Nathalie; Berry, Isabelle; Trotter, Yves; Baurès, Robin; Rosito, Maxime; Soler, Vincent; Peyrin, Carole; Cottereau, Benoit, R |
| Contributors: |
Centre de recherche cerveau et cognition (CERCO UMR5549); Centre National de la Recherche Scientifique (CNRS)-Université de Toulouse (EPE UT); Communauté d'universités et établissements de Toulouse (Comue de Toulouse)-Communauté d'universités et établissements de Toulouse (Comue de Toulouse)-Toulouse Mind & Brain Institut (TMBI); Université Toulouse - Jean Jaurès (UT2J); Communauté d'universités et établissements de Toulouse (Comue de Toulouse)-Communauté d'universités et établissements de Toulouse (Comue de Toulouse)-Université de Toulouse (EPE UT); Communauté d'universités et établissements de Toulouse (Comue de Toulouse)-Université Toulouse - Jean Jaurès (UT2J); Communauté d'universités et établissements de Toulouse (Comue de Toulouse)-Université de Toulouse (EPE UT); Communauté d'universités et établissements de Toulouse (Comue de Toulouse); Laboratoire de Psychologie et NeuroCognition (LPNC); Université Savoie Mont Blanc (USMB Université de Savoie Université de Chambéry )-Centre National de la Recherche Scientifique (CNRS)-Université Grenoble Alpes (UGA); CHU de Grenoble-Alpes - Centre Hospitalier Universitaire CHU Grenoble (CHUGA); Image & Pervasive Access Lab (IPAL); National University of Singapore (NUS)-Agency for science, technology and research Singapore (A*STAR)-Sorbonne Université (SU)-Centre National de la Recherche Scientifique (CNRS)-Institute for Infocomm Research - I²R Singapore; ANR-21-CE28-0021,ReViS-MD,Réorganisations des capacités visuo-cognitives chez les patients atteints de dégénérescence maculaire(2021); ANR-11-INBS-0006,FLI,France Life Imaging(2011) |
| Source: |
ISSN: 0146-0404. |
| Publisher Information: |
CCSD; Association for Research in Vision and Ophthalmology |
| Publication Year: |
2026 |
| Collection: |
Université Toulouse III - Paul Sabatier: HAL-UPS |
| Subject Terms: |
perceptual learning; neuroimaging; motion processing; aging; macular degeneration; [SDV.NEU.SC]Life Sciences [q-bio]/Neurons and Cognition [q-bio.NC]/Cognitive Sciences; [SDV.MHEP.OS]Life Sciences [q-bio]/Human health and pathology/Sensory Organs |
| Description: |
International audience ; PURPOSE: Macular degeneration (MD) is a disease affecting the central retina and significantly impairing vision. Given the absence of a cure, rehabilitation strategies are vital for enhancing visual perception.METHODS: This study introduces a perceptual learning (PL) protocol for MD patients, focusing on improving motion perception, a key ability for navigating environments and social interactions. Patients underwent four weeks of motion discrimination training, with pretraining and post-training functional magnetic resonance imaging scans to study the underlying neural mechanisms. We also assessed generalization to an untrained multiobject tracking task in a subset of participants. A control group, matched by age and gender with simulated scotomata, followed the same procedures.RESULTS: Results in both groups indicated improved motion discrimination and increased responses in the human middle temporal complex (hMT+), a critical neural hub for motion processing. Improvements in the multiobject tracking task suggested transferable learning effects.CONCLUSIONS. These findings highlight perceptual learning as a promising rehabilitation strategy for MD and potentially other eye conditions. |
| Document Type: |
article in journal/newspaper |
| Language: |
English |
| DOI: |
10.1167/iovs.67.3.52 |
| Availability: |
https://hal.science/hal-05568675; https://hal.science/hal-05568675v1/document; https://hal.science/hal-05568675v1/file/Michaud%20et%20al.%20%282026%29.pdf; https://doi.org/10.1167/iovs.67.3.52 |
| Rights: |
https://creativecommons.org/licenses/by/4.0/ ; info:eu-repo/semantics/OpenAccess |
| Accession Number: |
edsbas.6BA9B99B |
| Database: |
BASE |