| Title: |
ImmunoStart: preparing patients for immunosuppression |
| Authors: |
Martin, Charlotte; Muls, Vinciane; Brasseur, Celine; de Bellefon, Laurent Meric; Hoai, Xuan-Lan Lam; VAN DER HILST, Jeroen; Delforge, Marc; Di Romana, Silvana |
| Contributors: |
Martin, Charlotte/0000-0002-8995-6230; de Bellefon, Laurent Meric; VAN DER HILST, Jeroen; Martin, Charlotte; Delforge, Marc; Muls, Vinciane; Hoai, Xuan-Lan Lam; Di Romana, Silvana; Brasseur, Celine |
| Publisher Information: |
OXFORD UNIV PRESS |
| Publication Year: |
2022 |
| Collection: |
Document Server@UHasselt (Universiteit Hasselt) |
| Subject Terms: |
immune-mediated inflammatory disease; prevention; immunosuppression; vaccination; screening; latent |
| Description: |
Objectives. Patients with immune-mediated inflammatory disease (IMID) present an increased risk of infection. Here, we present the concept of a preventive consultation called ImmunoStart and the first results of its implementation in the care pathway of patients with IMID. Methods. Relevant information about vaccination history, tuberculosis exposure and other infectious risks were collected through blood sampling, complete anamnesis, chest X-ray and Mantoux test. During the ImmunoStart consultation, vaccination schedules, specific treatments and risk considerations were discussed. Results. Between October 2016 and February 2020, 437 patients were seen at an ImmunoStart consultation, mainly referred by rheumatologists (56%), dermatologists (25%) and gastroenterologists (18%). A total of 421 (96%) patients needed at least one vaccine (a mean of 3.3 vaccines per patient). Live attenuated vaccine was indicated for 45 patients (10%), requiring them to reduce or interrupt their immunosuppressive drug(s). Ninety-two patients (21%) were treated for latent tuberculosis infection. Conclusion. This preventive consultation provides a centralized and systematic setting for the direct management of patients with IMID in need of vaccination, treatment of latent disease and specific advice regarding their immunomodulating treatments. ; The authors thank Julie Massart, Khadra Massaoudi and Khadija Tarfi for their valuable help in coordinating and caring for ImmunoStart patients, as well as colleagues Christine Ellis, Charlotte De Volder and Thibaut Van Baelen for their help in the ImmunoStart consultation. They also thank Emile Freteur for her efficient work and support. C.M. created the ImmunoStart consultation in collaboration with V.M., C.B., L.M.B., X.L. and S.D.R. C.M. is the head of the ImmunoStart clinic. C.M. collected the data and drafted the initial manuscript. V.M., C.B., L.M.B., X.L., S.D.R. and J.V. reviewed and edited the manuscript and provided substantial comments. Funding: No specific funding was received from ... |
| Document Type: |
article in journal/newspaper |
| File Description: |
application/pdf |
| Language: |
English |
| ISSN: |
34909567 |
| Relation: |
Rheumatology advances in practice, 5 (3) (Art N° rkab092); https://hdl.handle.net/1942/37589; WOS:000807740000031 |
| DOI: |
10.1093/rap/rkab092 |
| Availability: |
https://hdl.handle.net/1942/37589; https://doi.org/10.1093/rap/rkab092 |
| Rights: |
The Author(s) 2021. Published by Oxford University Press on behalf of the British Society for Rheumatology. This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial License (https://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com ; info:eu-repo/semantics/openAccess |
| Accession Number: |
edsbas.6C4D78E7 |
| Database: |
BASE |