| Title: |
The histology of brain tumors for 67 331 children and 671 085 adults diagnosed in 60 countries during 2000-2014: a global, population-based study (CONCORD-3) |
| Authors: |
Girardi, Fabio; Rous, Brian; Stiller, Charles, A; Gatta, Gemma; Fersht, Naomi; Storm, Hans, H; Rodrigues, Jessica, R; Herrmann, Christian; Marcos-Gragera, Rafael; Peris-Bonet, Rafael; Valkov, Mikhail; Weir, Hannah, K; Woods, Ryan, R; You, Hui; Cueva, Patricia, A; De, Prithwish; Di Carlo, Veronica; Johannesen, Tom, Børge; Lima, Carlos, A; Lynch, Charles, F; Coleman, Michel, P; Allemani, Claudia; Bouzbid, S; Hamdi-Chérif, M; Zaidi, Z; Meguenni, K; Regagba, D; Bayo, S; Cheick Bougadari, T; Manraj, S, S; Bendahhou, K; Ladipo, A; Ogunbiyi, O, J; Ramaliba, T; Somdyala, N, I M; Chaplin, M, A; Moreno, F; Calabrano, G, H; Espinola, S, B; Carballo Quintero, B; Fita, R; Laspada, W, D; Ibañez, S, G; Mafra da Costa, A; de Souza, P, C F; del Pino, K; Laporte, C; Curado, M, P; de Oliveira, J, C; Veneziano, C, L A; Veneziano, D, B; Latorre, M, R D O; Tanaka, L, F; Rebelo, M, S; Santos, M, O; Azevedo E Silva, G; Galaz, J, C; Aparicio Aravena, M; Sanhueza Monsalve, J; Herrmann, D, A; Vargas, S; Herrera, V, M; Uribe, C, J; Bravo, L, E; Garcia, L, S; Arias-Ortiz, N, E; Morantes, D; Jurado, D, M; Yépez Chamorro, M, C; Delgado, S; Ramirez, M; Galán Alvarez, Y, H; Torres, P; Martínez-Reyes, F; Jaramillo, L; Quinto, R; Castillo, J; Mendoza, M; Yépez, J, G; Bhakkan, B; Deloumeaux, J; Joachim, C; Macni, J; Carrillo, R; Shalkow Klincovstein, J; Rivera Gomez, R; Perez, P; Poquioma, E; Tortolero-Luna, G; Zavala, D; Alonso, R; Barrios, E; Eckstrand, A; Nikiforuk, C; Noonan, G; Turner, D; Kumar, E; Zhang, B; Mccrate, F, R; Ryan, S; Macintyre, M; Saint-Jacques, N; Anam, A; Mcclure, C, A; Vriends, K, A; Bertrand, C; Latreille, J; Kozie, S; Stuart-Panko, H; Freeman, T; George, J, T; Avila, R, M; O’brien, D, K; Holt, A; Almon, L; Kwong, S; Morris, C; Rycroft, R; Mueller, L; Phillips, C, E; Brown, H; Cromartie, B; Schwartz, A, G; Vigneau, F; Levin, G, M; Wohler, B; Bayakly, R; Ward, K, C; Gomez, S, L; Mckinley, M; Cress, R; Green, M, D; Miyagi, K; Johnson, C, J; Ruppert, L, P; Bentler, S; Charlton, M, E; Huang, B; Tucker, T, C; Deapen, D; Liu, L; Hsieh, M, C; Wu, X, C; Schwenn, M; Stern, K; Gershman, S, T; Knowlton, R, C; Alverson, G; Weaver, T; Bushhouse, S; Rogers, D, B; Jackson-Thompson, J; Lemons, D; Zimmerman, H, J; Hood, M; Roberts-Johnson, J; Riddle, B; Rees, J, R; Pawlish, K, S; Stroup, A; Key, C; Wiggins, C; Kahn, A, R; Schymura, M, J; Radhakrishnan, S; Rao, C; Giljahn, L, K; Slocumb, R, M; Feld, A; Aird, K, G; Beran, T; Rubertone, J, J; Slack, S, J; Oh, J; Janes, T, A; Schwartz, S, M; Chiodini, S; Hurley, D, M; Whiteside, M, A; Rai, S; Williams, M, A; Herget, K; Sweeney, C; Johnson, A, T; Keitheri Cheteri, M, B; Migliore Santiago, P; Blankenship, S, E; Farley, S; Borchers, R; Malicki, R; Espinoza, J; Grandpre, J; Weir, Hanna, K; Wilson, R; Edwards, B, K; Mariotto, A; Wang, N; Yang, L; Chen, J, S; Zhou, Y; He, Y, T; Song, G, H; Gu, X, P; Mei, D; Mu, H, J; Ge, H, M; Wu, T, H; Li, Y, Y; Zhao, D, L; Jin, F; Zhang, J, H; Zhu, F, D; Junhua, Q; Yang, Y, L; Jiang, C, X; Biao, W; Wang, J; Li, Q, L; Yi, H; Zhou, X; Dong, J; Li, W; Fu, F, X; Liu, S, Z; Chen, J, G; Zhu, J; Li, Y, H; Lu, Y, Q; Fan, M; Huang, S, Q; Guo, G, P; Zhaolai, H; Wei, K; Chen, W-Q; Wei, W; Zeng, H; Demetriou, A, V; Mang, W, K; Ngan, K, C; Kataki, A, C; Krishnatreya, M; Jayalekshmi, P, A; Sebastian, P; George, P, S; Mathew, A; Nandakumar, A; Malekzadeh, R; Roshandel, G; Keinan-Boker, L; Silverman, B, G; Koyanagi, Y; Ito, H; Sato, M; Tobori, F; Nakata, I; Teramoto, N; Hattori, M; Kaizaki, Y; Moki, F; Sugiyama, H; Utada, M; Nishimura, M; Yoshida, K; Kurosawa, K; Nemoto, Y; Narimatsu, H; Sakaguchi, M; Kanemura, S; Naito, M; Narisawa, R; Miyashiro, I; Nakata, K; Maeda, A; Sato, S; Oki, I; Fukushima, N; Shibata, A; Iwasa, K; Ono, C; Matsuda, T; Nimri, O; Jung, K, W; Won, Y, J; Alawadhi, E; Elbasmi, A; Ab Manan, A; Adam, F; Nansalmaa, E; Tudev, U; Ochir, C; Al Khater, A, M; El Mistiri, M, M; Lim, G, H; Teo, Y, Y; Chiang, C, J; Lee, W, C; Buasom, R; Sangrajrang, S; Suwanrungruang, K; Vatanasapt, P; Daoprasert, K; Pongnikorn, D; Leklob, A; Sangkitipaiboon, S; Geater, S, L; Sriplung, H; Ceylan, O; Kög, I; Dirican, O; Köse, T; Gurbuz, T; Karaşahin, F, E; Turhan, D; Aktaş, U; Halat, Y; Eser, S; Yakut, C, I; Altinisik, M; Cavusoglu, Y; Türkköylü, A; Üçüncü, N; Hackl, M; Zborovskaya, A, A; Aleinikova, O, V; Henau, K; van Eycken, L; Valerianova, Z; Yordanova, M, R; Šekerija, M; Dušek, L; Zvolský, M; Steinrud Mørch, L; Wessel Skovlund, C; Innos, K; Mägi, M; Malila, N; Seppä, K; Jégu, J; Velten, M; Cornet, E; Troussard, X; Bouvier, A, M; Guizard, A, V; Bouvier, V; Launoy, G; Arveux, P; Maynadié, M; Mounier, M; Woronoff, A, S; Daoulas, M; Robaszkiewicz, M; Clavel, J; Goujon, S; Lacour, Brigitte; Baldi, I; Pouchieu, C; Amadeo, B; Coureau, G; Orazio, S; Monnereau, A; Preux, Pierre-Marie; Rharbaoui, F; Marrer, E; Trétarre, B; Colonna, M; Delafosse, P; Plouvier, S; Cowppli-Bony, A; Molinié, F; Bara, S; Ganry, O; Lapôtre-Ledoux, B; Grosclaude, P; Bossard, N; Uhry, Z; Estève, J; Stabenow, R; Wilsdorf-Köhler, H; Eberle, A; Luttmann, S; Löhden, I; Nennecke, A, L; Kieschke, J; Sirri, E; Justenhoven, C; Zeissig, S, R; Holleczek, B; Eisemann, N; Katalinic, A; Asquez, R, A; Kumar, V; Petridou, E; Ólafsdóttir, E, J; Tryggvadóttir, L; Clough-Gorr, K; Walsh, P, M; Sundseth, H; Mazzoleni, G; Vittadello, F; Coviello, E; Cuccaro, F; Galasso, R; Sampietro, G; Giacomin, A; Magoni, M; Ardizzone, A; D’argenzio, A; Castaing, M; Grosso, G; Lavecchia, A, M; Sutera Sardo, A; Gola, G; Gatti, L; Ricci, P; Ferretti, S; Dal Maso, L; Serraino, D; Celesia, M, V; Filiberti, R, A; Pannozzo, F; Melcarne, A; Quarta, F; Andreano, A; Russo, A, G; Carrozzi, G; Cirilli, C; Cavalieri D’oro, L; Rognoni, M; Fusco, M; Vitale, M, F; Usala, M; Cusimano, R; Mazzucco, W; Michiara, M; Sgargi, P; Boschetti, L; Chiaranda, G; Seghini, P; Maule, M, M; Merletti, F; Tumino, R; Mancuso, P; Vicentini, M; Cassetti, T; Sassatelli, R; Falcini, F; Giorgetti, S; Caiazzo, A, L; Cavallo, R; Cesaraccio, R; Pirino, D, R; Bella, F; Madeddu, A; Fanetti, A, C; Maspero, S; Carone, S; Mincuzzi, A; Candela, G; Scuderi, T; Gentilini, M, A; Piffer, S; Rosso, S; Barchielli, A; Caldarella, A; Bianconi, F; Stracci, F; Contiero, P; Tagliabue, G; Rugge, M; Zorzi, M; Beggiato, S; Brustolin, A; de Angelis, R; Zanetti, R; Maurina, A; Oniščuka, M; Mousavi, M; Lipunova, N; Vincerževskienė, I; Agius, D; Calleja, N; Siesling, S; Visser, O; Larønningen, S; Møller, B; Dyzmann-Sroka, A; Trojanowski, M; Góźdź, S; Mierzwa, T; Molong, L; Rachtan, J; Szewczyk, S; Błaszczyk, J; Kępska, K; Kościańska, B; Amunicka, R; Ostrowski, A; Zwierko, M; Kaczmarek, W; Maksimowicz, K, M; Purwin-Porowska, E; Reca, E; Wójcik-Tomaszewska, J; Czajkowska, E; Motnyk, M; Grądalska-Lampart, M; Radziszewska, A, U; Gos, A; Talerczyk, M; Wyborska, M; Didkowska, J, A; Wojciechowska, U; Bielska-Lasota, M; Forjaz de Lacerda, G; Rego, R, A; Carrito, B; Pais, A; Bento, M, J a T; Mayer-Da-Silva, A; Miranda, A; Blaga, L, M; Coza, D; Valkov, Mikhail, Y; Gusenkova, L; Lazarevich, O; Prudnikova, O; Vjushkov, D, M; Egorova, A, G; Orlov, A, E; Kudyakov, L, A; Pikalova, L, V; Adamcik, J; Safaei Diba, C; Primic-Žakelj, M; Zadnik, V; Gil, L; Lopez de Munain, A; Herrera, A, A; Rojas, D; Chillarón, R, J; Navarro, A, I M; Vilardell Gil, M, L; Molina, E; Sánchez Perez, M, J; Franch Sureda, P; Ramos Montserrat, M; Chirlaque, M, D; Navarro, C; Ardanaz, E; Guevara, M; Cañete-Nieto, A; Carulla, M; Galceran, J; Almela, F; Sabater, C; Khan, S; Pettersson, D; Dickman, P; Staehelin, K; Struchen, B; Egger Hayoz, C; Bouchardy, C; Schaffar, R; Rössle, M; Mousavi, S, M; Bulliard, J, L; Maspoli-Conconi, M; Kuehni, C, E; Redmond, S, M; Bordoni, A; Ortelli, L; Chiolero, A; Konzelmann, I; Matthes, K, L; Rohrmann, S; Broggio, J; Rashbass, J; Fitzpatrick, D; Gavin, A; Clark, D, I; Deas, A, J; Huws, D, W; Matz, M; Minicozzi, P; Montel, L; Nikšić, M; Ssenyonga, N; Stephens, R; Chalker, E; Smith, M; Walton, R; Qin Li, S; Dugdale, S; Moore, J; Philpot, S; Pfeiffer, R; Thomas, H; Stokes, B, C; Venn, A; Farrugia, H; Thursfield, V; Dowling, J; Currow, D; Fowler, C; Lewis, C |
| Contributors: |
London School of Hygiene and Tropical Medicine (LSHTM); University College London Hospitals NHS Foundation Trust London, UK (UCLH); Public Health England London; IRCCS Istituto Nazionale dei Tumori Milano; Registo Oncológico Regional-Sul; Instituto Português de Oncologia do Porto / Portuguese Oncology Institute of Porto (IPO Porto); Girona Cancer Registry - Catalan Institute of Oncology (RGG - ICO Girona); Stanford School of Medicine Stanford; Stanford Medicine; Stanford University-Stanford University; centre international de recherche sur l'environnement et le développement (CIRED); Centre de Coopération Internationale en Recherche Agronomique pour le Développement (Cirad)-École des hautes études en sciences sociales (EHESS)-AgroParisTech-École nationale des ponts et chaussées (ENPC)-Centre National de la Recherche Scientifique (CNRS); Epidemiology of childhood and adolescent cancer; Centre for Research in Epidemiology and Statistics; Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Paris Cité (UPCité)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Paris Cité (UPCité)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE); Registre National des Tumeurs Solides de l'Enfant (RNTSE); Centre Hospitalier Régional Universitaire de Nancy (CHRU Nancy); Centre Hospitalier Universitaire de Nancy (CHU Nancy); Neuroépidémiologie Tropicale (NET); CHU Limoges-Institut d'Epidémiologie Neurologique et de Neurologie Tropicale-Institut National de la Santé et de la Recherche Médicale (INSERM)-Institut Génomique, Environnement, Immunité, Santé, Thérapeutique (GEIST); Université de Limoges (UNILIM)-Université de Limoges (UNILIM); CHU Amiens-Picardie; CHirurgie, IMagerie et REgénération tissulaire de l’extrémité céphalique - Caractérisation morphologique et fonctionnelle - UR UPJV 7516 (CHIMERE); Université de Picardie Jules Verne (UPJV); Evaluative Epidemiology Unit; Fondazione IRCCS; Institut für Werkzeugmaschinen und Fertigungstechnik (IWF); Technische Universität Braunschweig = Technical University of Braunschweig Braunschweig; Childhood Cancer Research Group, University of Oxford |
| Source: |
ISSN: 1522-8517. |
| Publisher Information: |
CCSD; Oxford University Press (OUP) |
| Publication Year: |
2021 |
| Subject Terms: |
primary brain tumor; population-based cancer registries; histology; health care disparities; epidemiological study; International Classification of Diseases; MESH: Adult; MESH: Astrocytoma; MESH: Brain Neoplasms* / epidemiology; MESH: Child; MESH: Databases; Factual; MESH: Europe; MESH: Humans; MESH: Registries; [SDV.SPEE]Life Sciences [q-bio]/Santé publique et épidémiologie |
| Description: |
Auteurs : The CONCORD Working Group ; International audience ; Background: Global variations in survival for brain tumors are very wide when all histological types are considered together. Appraisal of international differences should be informed by the distribution of histology, but little is known beyond Europe and North America.Methods: The source for the analysis was the CONCORD database, a program of global surveillance of cancer survival trends, which includes the tumor records of individual patients from more than 300 population-based cancer registries. We considered all patients aged 0-99 years who were diagnosed with a primary brain tumor during 2000-2014, whether malignant or nonmalignant. We presented the histology distribution of these tumors, for patients diagnosed during 2000-2004, 2005-2009, and 2010-2014.Results: Records were submitted from 60 countries on 5 continents, 67 331 for children and 671 085 for adults. After exclusion of irrelevant morphology codes, the final study population comprised 60 783 children and 602 112 adults. Only 59 of 60 countries covered in CONCORD-3 were included because none of the Mexican records were eligible. We defined 12 histology groups for children, and 11 for adults. In children (0-14 years), the proportion of low-grade astrocytomas ranged between 6% and 50%. Medulloblastoma was the most common subtype in countries where low-grade astrocytoma was less commonly reported. In adults (15-99 years), the proportion of glioblastomas varied between 9% and 69%. International comparisons were made difficult by wide differences in the proportion of tumors with unspecified histology, which accounted for up to 52% of diagnoses in children and up to 65% in adults.Conclusions: To our knowledge, this is the first account of the global histology distribution of brain tumors, in children and adults. Our findings provide insights into the practices and the quality of cancer registration worldwide. |
| Document Type: |
article in journal/newspaper |
| Language: |
English |
| Relation: |
info:eu-repo/semantics/altIdentifier/pmid/33738488; PUBMED: 33738488; PUBMEDCENTRAL: PMC8485444 |
| DOI: |
10.1093/neuonc/noab067 |
| Availability: |
https://hal.science/hal-04044020; https://doi.org/10.1093/neuonc/noab067 |
| Accession Number: |
edsbas.6C624121 |
| Database: |
BASE |