| Title: |
Comparative In Vitro Activities of Ciprofloxacin, Clinafloxacin, Gatifloxacin, Levofloxacin, Moxifloxacin, and Trovafloxacin against Klebsiella pneumoniae , Klebsiella oxytoca , Enterobacter cloacae , and Enterobacter aerogenes Clinical Isolates with Alterations in GyrA and ParC Proteins |
| Authors: |
Brisse, Sylvain; Milatovic, Dana; Fluit, Ad C.; Verhoef, Jan; Martin, Nele; Scheuring, Sybille; Köhrer, Karl; Schmitz, Franz-Josef |
| Source: |
Antimicrobial Agents and Chemotherapy ; volume 43, issue 8, page 2051-2055 ; ISSN 0066-4804 1098-6596 |
| Publisher Information: |
American Society for Microbiology |
| Publication Year: |
1999 |
| Description: |
The in vitro activities of ciprofloxacin, clinafloxacin, gatifloxacin, levofloxacin, moxifloxacin, and trovafloxacin were tested against 72 ciprofloxacin-resistant and 28 ciprofloxacin-susceptible isolates of Klebsiella pneumoniae , Klebsiella oxytoca , Enterobacter cloacae , and Enterobacter aerogenes . Irrespective of the alterations in GyrA and ParC proteins, clinafloxacin exhibited greater activity than all other fluoroquinolones tested against K. pneumoniae and E. aerogenes . |
| Document Type: |
article in journal/newspaper |
| Language: |
English |
| DOI: |
10.1128/aac.43.8.2051 |
| DOI: |
10.1128/AAC.43.8.2051 |
| Availability: |
https://doi.org/10.1128/aac.43.8.2051; https://journals.asm.org/doi/pdf/10.1128/AAC.43.8.2051 |
| Rights: |
https://journals.asm.org/non-commercial-tdm-license |
| Accession Number: |
edsbas.6CAB9EB6 |
| Database: |
BASE |