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Effectiveness of additional or standalone corticosteroid injections compared to physical therapist interventions in rotator cuff tendinopathy: A systematic review and meta-analysis of randomized controlled trials

Title: Effectiveness of additional or standalone corticosteroid injections compared to physical therapist interventions in rotator cuff tendinopathy: A systematic review and meta-analysis of randomized controlled trials
Authors: Lazzarini, Stefano Giuseppe; Buraschi, Riccardo; Pollet, Joel; Bettariga, Francesco; Pancera, Simone; Pedersini, Paolo
Source: Research outputs 2022 to 2026
Publisher Information: Edith Cowan University, Research Online, Perth, Western Australia
Publication Year: 2025
Collection: Edith Cowan University (ECU, Australia): Research Online
Subject Terms: Injections; Physical Therapy Modalities; Rehabilitation; Rotator Cuff; Shoulder; Shoulder Impingement Syndrome; Tendinopathy; Medicine and Health Sciences; Rehabilitation and Therapy
Description: Importance. Rotator cuff tendinopathy represents the most prevalent cause of shoulder pain, the third most common musculoskeletal disorder after low back pain and knee pain. Objective. The objective of this study was to determine the effectiveness of corticosteroid injection(s), alone or in combination with anesthetic injection or any other physical therapist interventions, compared to physical therapist interventions alone in adults with rotator cuff tendinopathy. Design. This study was a systematic review and meta-analysis of randomized controlled trials. PubMed, EMBASE, Cumulative Index to Nursing and Allied Health Literature, Cochrane Central Register of Controlled Trials, Scopus, Web of Science, and Physiotherapy Evidence Database were searched from inception to March 2023. Meta-analysis using a random-effects model was performed. Risk of bias and certainty of the evidence for the primary outcomes were assessed using the Cochrane risk-of-bias tool and the Grading of Recommendations, Assessment, Development and Evaluation approach, respectively. The protocol was registered in the International Prospective Register of Systematic Reviews (CRD42021240882). Participants. Participants were adults with rotator cuff tendinopathy. Interventions. Corticosteroid injection(s), alone or in combination with anesthetic injection or with any other physical therapist interventions, was compared to physical therapist interventions alone. Main Outcomes. Pain, function, quality of life, patient-rated overall improvement, and adverse events were the main outcomes. Results. Fifteen randomized controlled trials (1785 participants) met the inclusion criteria. At short term, corticosteroid injection coupled with physical therapist interventions and compared to the same interventions alone might have resulted in some small to moderate improvements in pain and function. Conversely, corticosteroid injection alone seemed not to be more effective than physical therapist interventions in improving pain and function in most of the studies ...
Document Type: text
File Description: application/pdf
Language: unknown
DOI: 10.1093/ptj/pzaf006
Availability: https://ro.ecu.edu.au/ecuworks2022-2026/6129; https://doi.org/10.1093/ptj/pzaf006; https://ro.ecu.edu.au/context/ecuworks2022-2026/article/7130/viewcontent/Effectiveness_of_additional_or_standalone_corticosteroid_injections_compared_to_physical_therapist_interventions___AAM_version.pdf
Rights: http://creativecommons.org/licenses/by-nd/4.0/
Accession Number: edsbas.6CC6A6A2
Database: BASE