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Evidence for a neotropical origin of Leishmania

Title: Evidence for a neotropical origin of Leishmania
Authors: Noyes,HA; Morrison,DA; Chance,ML; Ellis,JT
Source: Memórias do Instituto Oswaldo Cruz v.95 n.4 2000
Publisher Information: Instituto Oswaldo Cruz, Ministério da Saúde
Publication Year: 2000
Collection: SciELO Brazil (Scientific Electronic Library Online)
Subject Terms: biogeography; Endotrypanum; Leishmania (Sauroleishmania); DNA polymerase; RNA polymerase
Description: Contradictory biogeographic hypotheses for either a Neotropical or a Palaearctic origin of the genus Leishmania have been proposed. Hypotheses constructed on the basis of biogeographic data must be tested against an independent dataset and cannot be supported by biogeographic data alone. In the absence of a fossil record for the Leishmania these two hypotheses were tested against a combined dataset of sequences from the DNA polymerase A catalytic subunit and the RNA polymerase II largest subunit. The phylogeny obtained provided considerable support for a Neotropical origin of the genus Leishmania and leads us to reject the hypothesis for a Palaearctic origin.
Document Type: article in journal/newspaper
File Description: text/html
Language: English
Availability: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762000000400021
Accession Number: edsbas.6CCD7F18
Database: BASE