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Safety and Immunogenicity of an Inactivated Hepatitis A Vaccine among HIV-Infected Subjects

Title: Safety and Immunogenicity of an Inactivated Hepatitis A Vaccine among HIV-Infected Subjects
Authors: Wallace, Mark R.; Brandt, Carolyn J.; Earhart, Kenneth C.; Kuter, Barbara J.; Grosso, Anthony D.; Lakkis, Hassan; Tasker, Sybil A.
Publisher Information: Oxford University Press
Publication Year: 2004
Collection: HighWire Press (Stanford University)
Subject Terms: Major Articles
Description: Background. Hepatitis A is a major health risk for many human immunodeficiency virus (HIV)-infected individuals. Vaccination is a potentially attractive measure to reduce the incidence of hepatitis A among this population, but data on its safety and immunogenicity are incomplete. Methods. Ninety HIV-uninfected adults received an inactivated hepatitis A vaccine (VAQTA; Merck), and 90 HIV-infected subjects were randomized, in double-blind fashion, to receive either the vaccine or placebo. The HIV-infected subjects were stratified by CD4 cell count, with 45 subjects having CD4 cell counts of ⩾300 cells/mm3 and 45 subjects having CD4 cell counts of
Document Type: text
File Description: text/html
Language: English
Relation: http://cid.oxfordjournals.org/cgi/content/short/39/8/1207; http://dx.doi.org/10.1086/424666
DOI: 10.1086/424666
Availability: http://cid.oxfordjournals.org/cgi/content/short/39/8/1207; https://doi.org/10.1086/424666
Rights: Copyright (C) 2004, Infectious Diseases Society of America
Accession Number: edsbas.6F5A2E72
Database: BASE