| Title: |
Alteration of the proximal aorta biophysical properties in patients with end-stage renal disease |
| Authors: |
Patrianakos, Alexander P; Karakitsos, Dimitrios; de Groot, Eric; Parthenakis, Frangiskos I.; Daphnis, Evgenios; Vardas, Panos E. |
| Publisher Information: |
British Medical Journal Publishing Group |
| Publication Year: |
2005 |
| Collection: |
HighWire Press (Stanford University) |
| Subject Terms: |
Original articles |
| Description: |
Objective : Altered biophysical properties of the aorta are a major risk factor for increased cardiac morbidity and mortality in patients with end-stage renal disease (ESRD). Aim : We present a novel, non-invasive echocardiographic application to assess the structural and functional properties of the complex composition of the proximal aorta. Methods : Seventy-one haemodialysis patients [age 61.3(9.3) years, dialysis duration 79.2(51.6) months] and 62 age-matched controls were studied. From the suprasternal view, the distance between ascending and descending aorta was measured with 2D-ultrasound; the aortic flow wave transit time was measured with pulsed-wave Doppler. M-mode echocardiography, with simultaneous blood pressure estimates, was used to assess the diameters of the aortic annulus and ascending aorta. Pulse pressure (PP), pulse wave velocity (PWV), pressure strain elastic modulus (PSEM), characteristic impedance (Zcs) and â-index were calculated. Results : Patients showed increased PP [68.3(7.2) v 51.4(5) mm Hg, p |
| Document Type: |
text |
| File Description: |
text/html |
| Language: |
English |
| Relation: |
http://heart.bmj.com/cgi/content/short/hrt.2004.055731v1; http://dx.doi.org/10.1136/hrt.2004.055731 |
| DOI: |
10.1136/hrt.2004.055731 |
| Availability: |
http://heart.bmj.com/cgi/content/short/hrt.2004.055731v1; https://doi.org/10.1136/hrt.2004.055731 |
| Rights: |
Copyright (C) 2005, BMJ Publishing Group Ltd |
| Accession Number: |
edsbas.6F8C79B7 |
| Database: |
BASE |