| Title: |
A Virion-Based Combination Vaccine Protects against Influenza and SARS-CoV-2 Disease in Mice |
| Authors: |
Chaparian, Ryan R.; Harding, Alfred T.; Hamele, Cait E.; Riebe, Kristina; Karlsson, Amelia; Sempowski, Gregory D.; Heaton, Nicholas S.; Heaton, Brook E. |
| Contributors: |
Schultz-Cherry, Stacey; HHS | NIH | National Institute of Allergy and Infectious Diseases |
| Source: |
Journal of Virology ; volume 96, issue 15 ; ISSN 0022-538X 1098-5514 |
| Publisher Information: |
American Society for Microbiology |
| Publication Year: |
2022 |
| Description: |
The rapid emergence of SARS-CoV-2 variants since the onset of the pandemic has highlighted the need for both periodic vaccination “boosts” and a platform that can be rapidly reformulated to manufacture new vaccines. In this work, we report an approach that can utilize current influenza vaccine manufacturing infrastructure to generate combination vaccines capable of protecting from both influenza virus- and SARS-CoV-2-induced disease. |
| Document Type: |
article in journal/newspaper |
| Language: |
English |
| DOI: |
10.1128/jvi.00689-22 |
| Availability: |
https://doi.org/10.1128/jvi.00689-22; https://journals.asm.org/doi/pdf/10.1128/jvi.00689-22 |
| Rights: |
https://doi.org/10.1128/ASMCopyrightv2 ; https://journals.asm.org/non-commercial-tdm-license |
| Accession Number: |
edsbas.6FDD2617 |
| Database: |
BASE |