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Obtaining and Characterizing Alginate/k-Carrageenan Hydrogel Cross-Linked with Adipic Dihydrazide

Title: Obtaining and Characterizing Alginate/k-Carrageenan Hydrogel Cross-Linked with Adipic Dihydrazide
Authors: Violeta Paşcalău; Violeta Popescu; George L. Popescu; Mircea C. Dudescu; Gheorghe Borodi; Adrian M. Dinescu; Marioara Moldovan
Source: Advances in Materials Science and Engineering, Vol 2013 (2013)
Publisher Information: Wiley
Publication Year: 2013
Collection: Directory of Open Access Journals: DOAJ Articles
Subject Terms: Materials of engineering and construction. Mechanics of materials; TA401-492
Description: The aim of this paper is obtaining and characterizing hydrogels based on different ratios of oxidized alginate (oA) and k-carrageenan (C), chemically cross-linked with adipic dihydrazide (adh). The alginate (A) was first oxidized with sodium metaperiodate in order to transform it into the dialdehyde derivative, a more reactive compound than alginate. A known procedure for oxidation of alginate with sodium metaperiodate in ethanol-water in order to improve alginate reactivity by transforming the hydroxyl end-groups into dialdehyde was used, preceded by a partially cleavage of the alginate chains. In the second stage, the mixture of dialdehydic derivative of oxidized alginate, k-carrageenan and glycerol subjected to reaction with adipic dihydrazide leads to a Semi-Interpenetrated Network covalently cross-linked alginate/k-carrageenan hydrogel (oACadh), based on the dihydrazone compound which is responsible for the chemical cross-linking. Pure alginate, k-carrageenan, oxidized alginate, adipic dihydrazide and the cross-linked hydrogel were characterized by: FTIR, XRD, and SEM.
Document Type: article in journal/newspaper
Language: English
Relation: http://dx.doi.org/10.1155/2013/380716; https://doaj.org/toc/1687-8434; https://doaj.org/toc/1687-8442; https://doaj.org/article/5f59db6ecde1485b88094d30aabe4201
DOI: 10.1155/2013/380716
Availability: https://doi.org/10.1155/2013/380716; https://doaj.org/article/5f59db6ecde1485b88094d30aabe4201
Accession Number: edsbas.709CFE3A
Database: BASE