| Title: |
Advanced glaucoma disease segmentation and classification with grey wolf optimized U-Net++ and capsule networks |
| Authors: |
Govindharaj, I.; Priya, W. Deva; Soujanya, K. L. S.; Senthilkumar, K. P.; Shalini, K. Shantha; Ravichandran, S. |
| Publisher Information: |
SPRINGER |
| Publication Year: |
2025 |
| Subject Terms: |
Ophthalmology |
| Description: |
Early detection of glaucoma represents a vital factor in securing vision while the disease retains its position as one of the central causes of blindness worldwide. The current glaucoma screening strategies with expert interpretation depend on complex and time-consuming procedures which slow down both diagnosis processes and intervention timing. This research adopts a complex automated glaucoma diagnostic system that combines optimized segmentation solutions together with classification platforms. The proposed segmentation approach implements an enhanced version of U-Net++ using dynamic parameter control provided by GWO to segment optic disc and cup regions in retinal fundus images. Through the implementation of GWO the algorithm uses wolf-pack hunting strategies to adjust parameters dynamically which enables it to locate diverse textural patterns inside images. The system uses a CapsNet capsule network for classification because it maintains visual spatial organization to detect glaucoma-related patterns precisely. The developed system secures an evaluation accuracy of 95.1% in segmentation and classification tasks better than typical approaches. The automated system eliminates and enhances clinical diagnostic speed as well as diagnostic precision. The tool stands out because of its supreme detection accuracy and reliability thus making it an essential clinical early-stage glaucoma diagnostic system and a scalable healthcare deployment solution.PurposeTo develop an advanced automated glaucoma diagnostic system by integrating an optimized U-Net++ segmentation model with a Capsule Network (CapsNet) classifier, enhanced through Grey Wolf Optimization Algorithm (GWOA), for precise segmentation of optic disc and cup regions and accurate glaucoma classification from retinal fundus images.MethodsThis study proposes a two-phase computer-assisted diagnosis (CAD) framework. In the segmentation phase, an enhanced U-Net++ model, optimized by GWOA, is employed to accurately delineate the optic disc and cup regions in fundus ... |
| Document Type: |
article in journal/newspaper |
| Language: |
unknown |
| ISSN: |
0165-5701 |
| Relation: |
Govindharaj, I. and Priya, W. Deva and Soujanya, K. L. S. and Senthilkumar, K. P. and Shalini, K. Shantha and Ravichandran, S. (2025) Advanced glaucoma disease segmentation and classification with grey wolf optimized U-Net++ and capsule networks. INTERNATIONAL OPHTHALMOLOGY, 45.0 (1). ISSN 0165-5701 |
| DOI: |
10.1007/s10792-025-03602-6 |
| Availability: |
https://ir.vmrfdu.edu.in/id/eprint/7242/; https://doi.org/10.1007/s10792-025-03602-6 |
| Accession Number: |
edsbas.71A5BADE |
| Database: |
BASE |