| Title: |
Lumbosacral plexopathy after short-course neoadjuvant radiotherapy for rectal cancer: A case report |
| Authors: |
Antony, Febin; Hooper, Davyd; Koenig, James; Nashed, Maged |
| Source: |
Journal of Cancer Research and Therapeutics ; volume 21, issue 1, page 243-246 ; ISSN 0973-1482 1998-4138 |
| Publisher Information: |
Ovid Technologies (Wolters Kluwer Health) |
| Publication Year: |
2024 |
| Description: |
Radiation-induced lumbosacral plexopathy (RILSP) is a rare complication associated with pelvic radiotherapy. Literature is scant about the incidence of RILSP after a neoadjuvant short-course radiotherapy (RT) in rectal cancer. In this report, we detail the symptoms, signs, and management of RILSP. Volumetric modulated arc therapy was used for delivering preoperative short-course RT in our rectal cancer patient. Six months after the completion of RT, the patient presented with symptoms of lower extremity motor and sensory impairment. An electrodiagnostic study revealed a pattern of bilateral sciatic nerve injury or a lower lumbosacral plexus abnormality. Magnetic resonance imaging showed radiation-related edema in the region of the lumbosacral plexus. Further blood and serum investigations ruled out other inflammatory and infectious differential diagnoses, thus a diagnosis of RILSP was made. He was initiated on analgesics and was also referred to physiotherapy and rehabilitation. After 2 months, his symptoms stabilized. |
| Document Type: |
article in journal/newspaper |
| Language: |
English |
| DOI: |
10.4103/jcrt.jcrt_1419_23 |
| Availability: |
https://doi.org/10.4103/jcrt.jcrt_1419_23; https://journals.lww.com/10.4103/jcrt.jcrt_1419_23 |
| Rights: |
http://creativecommons.org/licenses/by-nc-sa/4.0 |
| Accession Number: |
edsbas.71CBB9E1 |
| Database: |
BASE |