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TO STUDY CORRELATION OF INSULIN RESISTANCE WITH PHYSICAL ACTIVITY IN CHILDREN / ADOLESCENTS

Title: TO STUDY CORRELATION OF INSULIN RESISTANCE WITH PHYSICAL ACTIVITY IN CHILDREN / ADOLESCENTS
Authors: Ankanksha; Ashuma Sachdeva; Kapil Bhalla
Publisher Information: Zenodo
Publication Year: 2023
Collection: Zenodo
Subject Terms: Physical activity Obesity BMI Insulin Resistance
Description: Objective: IR is a pathological condition strongly associated with obesity and involved in the pathogenesis of T2D. The treatment of insulin resistant children is firstly targeted to lifestyle interventions. Homeostasis model assessment of insulin resistance (HOMA-IR) may be useful for early evaluation of insulin resistance in children and teenagers and could have a long-term benefit of preventive and diagnostic therapeutic intervention. Method: A cross-sectional study was performed on 80 children and adolescents age 5 to 14 years, 40 of them were apparently healthy with Body mass index (BMI) < 85th percentile 16 were overweight with BMI>85th percentile and below 95th percentile 24 were obese with > 95th percentile. Physical activity was classified on basis of WHO guidelines. Out of 80 children 33 were active and 47 were less active. After overnight fasting for 8 hr, blood samples were taken serum insulin and fasting blood glucose were analysed. Insulin resistance was assessed by homeostasis model of assessment. Result and Conclusion: Our results revealed altered values of HOMA-IR in children with high BMI and mean values were high in children with decrease physical activity. We concluded that more studies should be conducted to focus on preventing and identifying risk factors in children.
Document Type: article in journal/newspaper
Language: unknown
Relation: https://zenodo.org/records/7820460; oai:zenodo.org:7820460; https://doi.org/10.5281/zenodo.7820460
DOI: 10.5281/zenodo.7820460
Availability: https://doi.org/10.5281/zenodo.7820460; https://zenodo.org/records/7820460
Rights: Creative Commons Attribution 4.0 International ; cc-by-4.0 ; https://creativecommons.org/licenses/by/4.0/legalcode
Accession Number: edsbas.72D3E0CC
Database: BASE