| Title: |
Sugar-sweetened beverages, low/no-calorie beverages, fruit juices intake and risks of metabolic syndrome in adults: The SWEET project |
| Authors: |
Naomi, ND; Brouwer-Brolsma, EM; Buso, MEC; Soedamah-Muthu, SS; Mavrogianni, C; Harrold, JA; Halford, JCG; Raben, A; Geleijnse, JM; Manios, Y; Feskens, EJM |
| Publisher Information: |
Elsevier BV |
| Publication Year: |
2025 |
| Collection: |
The University of Liverpool Repository |
| Description: |
Background and aims: Metabolic syndrome (MetS) is an important determinant of cardiometabolic disease development, with excessive sugar intake as one of the key modifiable risk factors. However, evidence on the association between sugar-sweetened beverages (SSB), their replacement by low/no caloric beverages (LNCB), and MetS development is still limited. Methods and results: Data from participants’ of Lifelines (n = 58 220), NQPlus (n = 1094) and Feel4Diabetes (n = 342) were prospectively analysed. Dose-response associations were investigated using restricted cubic spline analyses (Lifelines). Cox proportional hazard regression analysis with robust variance was used to quantify associations between intakes of SSB, fruit juices (FJ) and LNCB and MetS incidence; data were pooled using random-effects models. Associations were adjusted for demographic, lifestyle and other dietary factors. In Lifelines, NQPlus, and Feel4Diabetes, 3853 (7 %), 47 (4 %), and 39 (11 %) participants developed MetS, respectively. Pooled analyses showed that each additional serving of SSB was associated with a 6 % higher risk of MetS (95%CI 1.02–1.10). A J-shaped association was observed for FJ and MetS, with a significant inverse association at moderate intake levels (IPR 0.89, 95 % CI 0.82–0.96). LNCB intake was not associated with MetS (IPR 1.59, 95%CI 0.74–2.43), but findings across studies were inconsistent (I 2 94 %, p-value |
| Document Type: |
article in journal/newspaper |
| File Description: |
application/pdf |
| Language: |
English |
| ISSN: |
0939-4753 |
| Relation: |
https://livrepository.liverpool.ac.uk/3195222/1/PIIS0939475324003636.pdf; Collapse authors list. Naomi, ND orcid:0000-0001-8141-4907 , Brouwer-Brolsma, EM, Buso, MEC, Soedamah-Muthu, SS orcid:0000-0002-8830-3502 , Mavrogianni, C, Harrold, JA orcid:0000-0002-0899-4586 , Halford, JCG, Raben, A orcid:0000-0001-5229-4491 , Geleijnse, JM orcid:0000-0001-7638-0589 , Manios, Y orcid:0000-0001-6486-114X et al (show 1 more authors) and Feskens, EJM orcid:0000-0001-5819-2488 (2025) Sugar-sweetened beverages, low/no-calorie beverages, fruit juices intake and risks of metabolic syndrome in adults: The SWEET project Nutrition Metabolism and Cardiovascular Diseases, 35 (2). 103744-. ISSN 0939-4753, 1590-3729 |
| DOI: |
10.1016/j.numecd.2024.09.014 |
| Availability: |
https://livrepository.liverpool.ac.uk/3195222/; https://doi.org/10.1016/j.numecd.2024.09.014; https://livrepository.liverpool.ac.uk/3195222/1/PIIS0939475324003636.pdf |
| Rights: |
cc_by_4 |
| Accession Number: |
edsbas.7396265D |
| Database: |
BASE |