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Impact of Therapeutic Radioactive Iodine on the Recurrence of Papillary Thyroid Cancer With Extranodal Extension in Metastatic Lymph Nodes: A Propensity Score-matched Analysis

Title: Impact of Therapeutic Radioactive Iodine on the Recurrence of Papillary Thyroid Cancer With Extranodal Extension in Metastatic Lymph Nodes: A Propensity Score-matched Analysis
Authors: Kim, Hye In; Kim, Boram; Hyeon, Jiyeon; Ko, Nak Gyeong; Jin, Mihyeon; Cho, Jung Hwan; Han, Ji Min; Suh, Sunghwan; Bae, Ji Cheol; Chung, Man Ki; Choe, Jun-Ho; Kim, Sun Wook; Chung, Jae Hoon; Oh, Young Lyun; Kim, Kyunga; Kim, Tae Hyuk; Choi, Joon Young
Source: Clinical Nuclear Medicine ; volume 50, issue 9, page 830-839 ; ISSN 0363-9762 1536-0229
Publisher Information: Ovid Technologies (Wolters Kluwer Health)
Publication Year: 2025
Description: Purpose: Radioactive iodine therapy (RAI) ≥100 mCi (3.7 GBq) is commonly recommended for papillary thyroid cancer (PTC) patients with extranodal extension (ENE). However, no study has evaluated whether RAI ≥100 mCi is effective in reducing the recurrence of PTC with ENE. Methods: This retrospective cohort study enrolled 191 PTC patients with ENE who underwent total thyroidectomy and RAI. Recurrence according to RAI activity (
Document Type: article in journal/newspaper
Language: English
DOI: 10.1097/rlu.0000000000005940
DOI: 10.1097/RLU.0000000000005940
Availability: https://doi.org/10.1097/rlu.0000000000005940; https://journals.lww.com/10.1097/RLU.0000000000005940
Accession Number: edsbas.73A28C3E
Database: BASE