| Title: |
Reduced Ejection Fraction in Elite Endurance Athletes: Clinical and Genetic Overlap With Dilated Cardiomyopathy |
| Authors: |
Claessen, Guido; De Bosscher, Ruben; Janssens, Kristel; Young, Paul; Dausin, Christophe; Claeys, Mathias; Claus, Piet; Goetschalckx, Kaatje; Bogaert, Jan; Mitchell, Amy M.; Flannery, Michael D.; Elliott, Adrian D.; Yu, Chenglong; Ghekiere, Olivier; Robyns, Tomas; Van De Heyning, Caroline M.; Sanders, Prashanthan; Kalman, Jonathan M.; Ohanian, Monique; Soka, Magdalena; Rath, Emma; Giannoulatou, Eleni; Johnson, Renee; Lacaze, Paul; Herbots, Lieven; Willems, Rik; Fatkin, Diane; Heidbuchel, Hein; La Gerche, André; Van Soest, Sofie; Bekhuis, Youri; Pauwels, Rik; De Paepe, Jarne; Hespel, Peter; Dymarkowski, Steven; Dresselaers, Tom; Miljoen, Hielko; Favere, Kasper; Paelinck, Bernard; Vermeulen, Dorien; Witvrouwen, Isabel; Hansen, Dominique; Op’t Eijnde, Bert; Thijs, Daisy; Vanvoorden, Peter; Lefebvre, Kristof; D’Ambrosio, Paolo; Rowe, Stephanie; Paratz, Elizabeth; Brosnan, Maria J. |
| Source: |
Circulation ; volume 149, issue 18, page 1405-1415 ; ISSN 0009-7322 1524-4539 |
| Publisher Information: |
Ovid Technologies (Wolters Kluwer Health) |
| Publication Year: |
2024 |
| Description: |
BACKGROUND: Exercise-induced cardiac remodeling can be profound, resulting in clinical overlap with dilated cardiomyopathy, yet the significance of reduced ejection fraction (EF) in athletes is unclear. The aim is to assess the prevalence, clinical consequences, and genetic predisposition of reduced EF in athletes. METHODS: Young endurance athletes were recruited from elite training programs and underwent comprehensive cardiac phenotyping and genetic testing. Those with reduced EF using cardiac magnetic resonance imaging (defined as left ventricular EF |
| Document Type: |
article in journal/newspaper |
| Language: |
English |
| DOI: |
10.1161/circulationaha.122.063777 |
| DOI: |
10.1161/CIRCULATIONAHA.122.063777 |
| Availability: |
https://doi.org/10.1161/circulationaha.122.063777; https://www.ahajournals.org/doi/full/10.1161/CIRCULATIONAHA.122.063777 |
| Rights: |
https://creativecommons.org/licenses/by/4.0/ |
| Accession Number: |
edsbas.742C7C9 |
| Database: |
BASE |