| Title: |
Incidence, prevalence and clinical presentation of inflammatory bowel diseases in Northern France: a 30-year population-based study |
| Authors: |
Sarter, Hélène; Crétin, Thibaut; Savoye, Guillaume; Fumery, Mathurin; Leroyer, Ariane; Dauchet, Luc; Paupard, Thierry; Coevoet, Hugues; Wils, Pauline; Richard, Nicolas; Turck, Dominique; Ley, Delphine; Gower-Rousseau, Corinne; Agoute, Eric; Al Ghossaini, Najib; Al Hameedi, Raied; Al Khatib, Myriam; Al Turk, Saria; Andre, Jean-Marie; Antoine, Matthieu; Antonietti, Michel; Aouakli, Amar; Armengol-Debeir, Laura; Aroichane, Ibrahim; Assi, Fadi; Auxenfants, Eric; Avram, Alina; Azzouzi, Kassem; Bankovski, Damyan; Barbry, Bernard; Bardoux, Nicolas; Baron, Philippe; Baudet, Anne; Bayart, Pauline; Bazin, Brice; Bebahani, Arash; Becqwort, Jean-Pierre; Ben Ali, Houssem; Ben Soussan, Emmanuel; Benard, Coralie; Benet, Vincent; Benguigui, Corinne; Bental, Abdeslam; Bentaleb-Bellati, Sara; Berkelmans, Isabelle; Bernet, Jacques; Bernou, Karine; Bertiaux-Vandaele, Nathalie; Bertot, Pauline; Bertrand, Valérie; Biloud, Emilie; Biron, Nathalie; Bismuth, Benjamin; Blanchard, Cyril; Bleuez, Maurice; Blondel, Fabienne; Blondin, Valérie; Bobula, Marius; Bohont, Philippe; Boivin, Eléonore; Djemah, Vanessa Bon; Boniface, Eric; Bonniere, Philippe; Bonvarlet, Pierre; Boruchowicz, Arnaud; Bostvironnois, Raoul; Boualit, Médina; Bouazza, Ahlem; Bouche, Bruno; Boudailler, Christian; Bourgeaux, Claude; Bourgeois-Fumery, Morgane; Bourguet, Arnaud; Bourienne, Agnès; Boutaleb, Hamza; Bouthors, Alexis; Branche, Julien; Brazier, Franck; Bridenne, Marie; Brihier, Hélène; Bril, Laura; Bulois, Philippe; Burgiere, Pierre; Butel, Joël; Canva, Jean-Yves; Canva-Delcambre, Valérie; Cardot, Florence; Carette, Sandrine; Carpentier, Pierre; Cassagnou, Michel; Cassar, Jean-François; Castex, François; Catala, Pascale; Cattan, Stéphane; Catteau, Sylviane; Caujolle, Bernard; Cayron, Gérard; Chandelier, Catherine; Charpentier, Cloé; Chavance-Thelu, Marthe; Cheny, Agathe; Chirita, Dinu; Choteau, Antoine; Claerbout, Jean-François; Clergue, Pierre-Yves; Cohen, Gil; Colin, Marie; Collet, Régis; Colombel, Jean-Frédéric; Coopman, Stéphanie; Cordiez, Lucie; Cortot, Antoine; Corvisart, Jean; Couttenier, Frédéric; Crinquette, Jean-François; Crombe, Valérie; Daoudi, Abdelhakim; Dapvril, Vincent; Davion, Thierry; Decoster, Sébastien; Defontaine, Laurent; Degrave, Nicolas; Dejaeger, Aurélien; Delcenserie, Richard; Deleplanque, Marine; Delesalle, Dorothée; Delette, Olivier; Delgrange, Thierry; Delhoustal, Laurence; Delmotte, Jean-Stéphane; Demmane, Sabri; Deregnaucourt, Guy; Deschepper, Constance; Desechalliers, Jean-Pierre; Desmet, Patrick; Desreumaux, Pierre; Desseaux, Gérard; Desurmont, Philippe; Devienne, Alain; Devouge, Eve; Devroux, Alex; Dewailly, Arnaud; Dharancy, Sébastien; Di Fiore, Aude; Diaz, Emmanuel; Djeddi, Djamal-Dine; Djedir, Rachid; Doleh, Wissam; Dreher-Duwat, Marie-Laure; Dubois, Richard; Duburque, Clothilde; Ducrot, Frédéric; Ducrotte, Philippe; Dufilho, André; Duhamel, Christian; Dumant-Forest, Caroline; Dupas, Jean-Louis; Dupont, Frédéric; Duranton, Yves; Duriez, Arnaud; Duveau, Nicolas; El Farisi, Mohammadi; El Hachkar, Khalil; Elie, Caroline; Elie-Legrand, Marie-Claire; Eoche, Matthieu; Essmaeel, Essmaeel; Evrard, Dominique; Evrard, Jean-Paul; Fatome, Armelle; Fellah-Sekkai, Karima; Filoche, Bernard; Finet, Laurent; Flahaut, Mathilde; Flamme, Camille; Foissey, David; Fournier, Peggy; Foutrein, Philippe; Foutrein-Comes, Marie-Christine; Frere, Thierry; Galand, Julie; Gallais, Philippe; Gamblin, Claudine; Ganga, Serge; Gerard, Romain; Geslin, Guillaume; Gheyssens, Yves; Ghrib, Salah; Gilbert, Thierry; Gillet, Bénédicte; Godart, Denis; Godchaux, Jean-Michel; Goeguebeur, Guetty; Goria, Odile; Gottrand, Frédéric; Gower, Philippe; Grados, Lucien; Grandmaison, Brigitte; Groux, Marion; Guedon, Claire; Guerbeau, Loïc; Gueroult-Dero, Mathilde; Guillard, Jean-François; Guillem, Laurence; Guillemot, François; Guimber, Dominique; Haddouche, Baya; Hautefeuille, Vincent; Hecketsweiller, Philippe; Hecquet, Geneviève; Hedde, Jean-Pierre; Hellal, Hassina; Henneresse, Pierre-Emmanuel; Heraud, Michel; Herve, Sophie; Heyman, Bruno; Hochain, Patrick; Houcke, Philippe; Houssin-Baillly, Lucie; Huguenin, Bruno; Iobagiu, Silviu; Istanboli, Shata; Ivanovic, Alexsandar; Iwanicki-Caron, Isabelle; Janicki, Eric; Jarry, Marine; Bart, Charlotte Jean; Jonas, Claude; Jougon, Julia; Jouvenet, Anne; Kassar, Naeim; Katherin, Fadi; Kerleveo, Alfred; Khachfe, Ali; Kiriakos, Alfred; Kiriakos, Jean; Klein, Olivier; Kohut, Matthieu; Kornhauser, Richard; Koutsomanis, Demetrios; Laberenne, Jean-Eric; Lacotte, Eric; Laffineur, Guy; Lagarde, Marine; Lahaye, Anouck; Lalanne, Arnaud; Lalieu, Ambroise; Lannoy, Pierre; Lapchin, José; Laprand, Michel; Laude, Denis; Le Couteulx, Christian; Le Goffic, Charles; Le Grix, Alain; Le Mouel, Jean-Philippe; Le Roy, Pauline; Leblanc, Rachida; Lecieux, Paul; Lecleire, Stéphane; Leclerc, Nathalie; Ledent, Jean; Lefebvre, Jean; Lefilliatre, Pascale; Legrand, Céline; Lelong, Patrick; Leluyer, Bernard; Lemaitre, Caroline; Lepileur, Lucie; Leplat, Antoine; Lepoutre-Dujardin, Elodie; Leppeut, Gabriel; Leroi, Henri; Leroy, Maryvonne; Lesage, Benoît; Lesage, Jocelyn; Lesage, Xavier; Lescanne-Darchis, Isabelle; Lescut, Dominique; Leurent, Bruno; Lhermie, Michel; Libier, Louise; Lisambert, Bernard; Loge, Isabelle; Loreau, Julien; Louvet, Alexandre; Lozinguez, Joséphine; Lubrez, Henri; Lucidarme, Damien; Lugand, Jean-Jacques; Macaigne, Olivier; Maetz, Denis; Maillard, Dominique; Mancheron, Hubert; Manolache, Olivia; Marks-Brunel, Anne-Bérengère; Marre, Charline; Marti, Raymond; Marzloff, Eric; Mathurin, Philippe; Mauillon, Jacques; Maunoury, Vincent; Maupas, Jean-Luc; Medam Djomo, Michèle-Ange; Melchior, Chloé; Melki, Ziad; Mesnard, B.; Metayer, Patrice; Methari, Lofti; Meurisse, Franck; Michaud, Laurent; Modaine, Patricia; Monthe, Angélique; Morel, Loïk; Morin, Mathilde; Mortier, Pierre-Eugène; Mortreux, Perrine; Mouterde, Olivier; Mozziconaci, Nicolas; Mudry, Jean; Nachuri, Maria; Ngo, Minh Dung; Khac, Eric N'Guyen; Notteghem, Bertrand; Ollevier, Vincent; Ouraghi, Atika; Oussadou, Barriza; Ouvry, Dominique; Paillot, Bernard; Painchart, Claire; Panien-Claudot, Nicole; Paoletti, Christian; Papazian, Arsène; Parent, Bruno; Paris, Jean-Claude; Patrier, Philippe; Pauwels, Bernard; Pauwels, Mathieu; Petit, Richard; Piat, Muriel; Piotte, Sandrine; Plane, Christophe; Plouvier, Bernard; Pollet, Eric; Pommelet, Pierre; Pop, Daniela; Pordes, Charlotte; Pouchain, Gérard; Prades, Philippe; Prevost, Jean-Christophe; Pruit, Manon; Quartier, Gilles; Queuniet, Anne-Marie; Quinton, Jean-François; Rabache, Alain; Raclot, Gilles; Ratajczyk, Sébastien; Reix, Nicole; Renaut-Vantroys, Thibaud; Revillion, Marine; Riachi, Ghassan; Riault, Clémentine; Richez, Cécile; Rimbert, Benoît; Robinson, Philippe; Rodriguez, Juan Daniel; Roger, Jean; Roux, Jean-Marc; Rudelli, Alain; Saingier, Clémence; Schlossberg, Patrick; Sefrioui, David; Segrestin, Michel; Seguy, David; Seminur, Célik; Sevenet, François; Silvie, Jean; Spyckerelle, Claire; Talbodec, Nathalie; Tavernier, Noémie; Tchandeu, Henriette; Techy, Aurore; Thelu, Jean-Luc; Thiebault, Henri; Thorel, Jean-Marie; Thuillier, Christophe; Tielman, Guillaume; Tode, Manuella; Tonnel, Jean; Touchais, Jean-Yves; Toulemonde-Huguet, Audrey; Toumelin, Pierre; Touze, Yvan; Tran, Léa; Tranvouez, Jean-Luc; Triki, Nadia; Turpin, Justine; Vaillant, Eric; Valmage, Claude; Vanco, Dominique; Vandaele-Bertiaux, Nathalie; Vandamme, Hélène; Eeken, Elise Vander; Vanderbercq, Etienne; Vandermollen, Philippe; Vandevenne, Philippe; Vandeville, Lionel; Vandewalle, Alain; Vanhoove, Jean-Pierre; Vanrenterghem, Audrey; Vanveuren, Charlotte; Vasies, Iona; Verbiese, Guy; Verlynde, Juliette; Vermelle, Philippe; Verne, Christine; Vernier-Massouille, Gwenola; Vezelier-Cocq, Perrine; Viart, Juliette; Vigneron, Benoît; Vincendet, Marc; Viot, Jacques; Voiment, Y.M.; Wallez, Jean-Yves; Wantier, Michel; Wartel, Faustine; Weber, Jean-Christian; Willocquet, Jean-Louis; Wizla, Nathalie; Wolschies, Eric; Yimfor, Tajiogue; Zahara, Oana; Zalar, Alberto; Zaoui, Sonia; Zellweger, Anne |
| Contributors: |
Centre Hospitalier Régional Universitaire CHU Lille CHRU Lille; Institute for Translational Research in Inflammation - U 1286 INFINITE; Service d'Hépato-Gastroentérologie CHU Rouen; Nutrition, Inflammation et axe Microbiote-Intestin-Cerveau ADEN; Université de Rouen Normandie UNIROUEN; Institute for Research and Innovation in Biomedicine IRIB; Périnatalité et Risques Toxiques - UMR INERIS_I 1 UPJV PERITOX; Service d'Hépato Gastroenterologie CHU Amiens-Picardie; Facteurs de Risque et Déterminants Moléculaires des Maladies liées au Vieillissement - U 1167 RID-AGE; Hôpital privé les Bonnettes Arras; Hôpital universitaire Robert Debré Reims CHU Reims; CHU Amiens-Picardie; Groupe de Recherche sur l'alcool et les pharmacodépendances - UMR INSERM_S 1247 UPJV GRAP |
| Publisher Information: |
Elsevier |
| Publication Year: |
2024 |
| Collection: |
LillOA (Lille Open Archive - Université de Lille) |
| Subject Terms: |
Crohn’s disease; Incidence; Inflammatory bowel disease; Population-based registry; Prevalence; Ulcerative colitis |
| Description: |
Background: In industrialized countries, the incidence of inflammatory bowel disease (IBD) appears stabilized. This study examined the incidence and phenotype of IBD in Northern France over a 30-year period.Methods: Including all IBD patients recorded in the EPIMAD population-based registry from 1988 to 2017 in Northern France, we described the incidence and clinical presentation of IBD according to age, sex and time.Findings: A total of 22,879 incident IBD cases were documented (59% (n = 13,445) of Crohn's disease (CD), 38% (n = 8803) of ulcerative colitis (UC), 3% (n = 631) of IBD unclassified (IBDU)). Over the study period, incidence of IBD, CD and UC was 12.7, 7.2 and 5.1 per 105 person-years, respectively. The incidence of CD increased from 5.1/105 in 1988-1990 to 7.9/105 in 2015-2017 (annual percent change (APC): +1.9%, p < 0.0001). The incidence of UC increased from 4.5/105 to 6.1/105 (APC: +1.3%, p < 0.0001). The largest increase was observed in children (+4.3% in CD, p < 0.0001; +5.4% in UC, p < 0.0001) followed by young adults aged 17-39 years (+1.9% in CD, p < 0.0001; +1.5% in UC, p < 0.0001). The increase in UC incidence was significantly higher in women than in men (+1.9% in women, +0.8% in men; p = 0.006). We estimated that in our area, by 2030, nearly 0.6% of the population will have IBD.Interpretation: The persistent increase of IBD incidence among children and young adults but also in women with UC in Northern France, suggests the persistence of substantial predisposing environmental factors. ; 47 |
| Document Type: |
article in journal/newspaper |
| File Description: |
application/rdf+xml; charset=utf-8; application/octet-stream |
| Language: |
English |
| Relation: |
The Lancet Regional Health - Europe; http://hdl.handle.net/20.500.12210/118330 |
| Availability: |
https://hdl.handle.net/20.500.12210/118330 |
| Rights: |
Attribution 3.0 United States ; info:eu-repo/semantics/openAccess |
| Accession Number: |
edsbas.75EBC6A2 |
| Database: |
BASE |