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Childhood intermittent and persistent rhinitis prevalence and climate and vegetation: A global ecologic analysis

Title: Childhood intermittent and persistent rhinitis prevalence and climate and vegetation: A global ecologic analysis
Authors: Fuertes, E.; Butland, B.; Ross Anderson, H.; Carlsten, C.; Strachan, D.; Brauer, M.; ISAAC Phase Three Study Group; LA GRUTTA, Stefania
Contributors: Fuertes, E.; Butland, B.; Ross Anderson, H.; Carlsten, C.; Strachan, D.; Brauer, M.; ISAAC Phase Three Study Group; La Grutta S.
Publisher Information: American College of Allergy, Asthma and Immunology
Publication Year: 2014
Collection: IRIS Università degli Studi di Palermo
Subject Terms: Adolescent; Asthma; Child; Eczema; Human; Plant; Questionnaire; Rhinitis; Allergic; Perennial; Seasonal; Climate Change; Immunology and Allergy; Pulmonary and Respiratory Medicine; Medicine (all)
Description: Background: The effect of climate change and its effects on vegetation growth, and consequently on rhinitis,are uncertain.Objective: To examine between- and within-country associations of climate measures and the normalizeddifference vegetation index with intermittent and persistent rhinitis symptoms in a global context.Methods: Questionnaire data from 6- to 7-year-olds and 13- to 14-year-olds were collected in phase 3 of theInternational Study of Asthma and Allergies in Childhood. Associations of intermittent (>1 symptom reportbut not for 2 consecutive months) and persistent (symptoms for -2 consecutive months) rhinitis symptomprevalences with temperature, precipitation, vapor pressure, and the normalized difference vegetation indexwere assessed in linear mixed-effects regression models adjusted for gross national income and populationdensity. The mean difference in prevalence per 100 children (with 95% confidence intervals [CIs]) perinterquartile range increase of exposure is reported.Results: The country-level intermittent symptom prevalence was associated with several country-levelclimatic measures, including the country-level mean monthly temperature (6.09-C; 95% CI, 2.06e10.11-C per 10.4-C), precipitation (3.10 mm; 95% CI, 0.46e5.73 mm; per 67.0 mm), and vapor pressure(6.21 hPa; 95% CI, 2.17e10.24 hPa; per 10.4 hPa) among 13- to 14-year-olds (222 center in 94 countries).The center-level persistent symptom prevalence was positively associated with several center-level climaticmeasures. Associations with climate were also found for the 6- to 7-year-olds (132 center in 57countries).Conclusion: Several between- and within-country spatial associations between climatic factors and intermittentand persistent rhinitis symptom prevalences were observed. These results provide suggestive evidencethat climate (and future changes in climate) may influence rhinitis symptom prevalence.
Document Type: article in journal/newspaper
Language: English
Relation: info:eu-repo/semantics/altIdentifier/pmid/25065574; info:eu-repo/semantics/altIdentifier/wos/WOS:000343113400008; volume:113; issue:4; firstpage:386; lastpage:392.e9; numberofpages:16; journal:ANNALS OF ALLERGY ASTHMA & IMMUNOLOGY; http://hdl.handle.net/10447/125034; http://www.elsevier.com/wps/find/journaldescription.reviewers/722283/description#description
DOI: 10.1016/j.anai.2014.06.021
Availability: http://hdl.handle.net/10447/125034; https://doi.org/10.1016/j.anai.2014.06.021; http://www.elsevier.com/wps/find/journaldescription.reviewers/722283/description#description
Rights: info:eu-repo/semantics/openAccess
Accession Number: edsbas.765A2DE7
Database: BASE