| Title: |
Functional effects of chimeric antigen receptor co-receptor signaling domains in human regulatory T cells |
| Authors: |
Dawson, Nicholas A. J.; Rosado-Sánchez, Isaac; Novakovsky, German E.; Fung, Vivian C. W.; Huang, Qing; McIver, Emma; Sun, Grace; Gillies, Jana; Speck, Madeleine; Orban, Paul C.; Mojibian, Majid; Levings, Megan K. |
| Contributors: |
Canadian Institutes of Health Research; TxCell S.A. |
| Source: |
Science Translational Medicine ; volume 12, issue 557 ; ISSN 1946-6234 1946-6242 |
| Publisher Information: |
American Association for the Advancement of Science (AAAS) |
| Publication Year: |
2020 |
| Description: |
Comparison of 10 co-receptor variant CARs revealed a requirement for CD28wt for optimal suppression by human regulatory T cells. |
| Document Type: |
article in journal/newspaper |
| Language: |
English |
| DOI: |
10.1126/scitranslmed.aaz3866 |
| Availability: |
https://doi.org/10.1126/scitranslmed.aaz3866; https://syndication.highwire.org/content/doi/10.1126/scitranslmed.aaz3866; https://www.science.org/doi/pdf/10.1126/scitranslmed.aaz3866 |
| Accession Number: |
edsbas.769EEBDB |
| Database: |
BASE |