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Oral anti-coagulants use in Chinese hospitalized patients with atrial fibrillation

Title: Oral anti-coagulants use in Chinese hospitalized patients with atrial fibrillation
Authors: Jing Lin; Deyong Long; Chenxi Jiang; Caihua Sang; Ribo Tang; Songnan Li; Wei Wang; Xueyuan Guo; Man Ning; Zhaoqing Sun; Na Yang; Yongchen Hao; Jun Liu; Jing Liu; Xin Du; Louise Morgan; Gregg C. Fonarow; Sidney C. Smith, Jr; Gregory Y.H. Lip; Dong Zhao; Jianzeng Dong; Changsheng Ma; On behalf of CCC-AF investigators; Rongman Jia; Xiuyuan Hao
Source: Chinese Medical Journal, Vol 137, Iss 2, Pp 172-180 (2024)
Publisher Information: Wolters Kluwer
Publication Year: 2024
Collection: Directory of Open Access Journals: DOAJ Articles
Subject Terms: Medicine
Description: Background:. Oral anti-coagulants (OAC) are the intervention for the prevention of stroke, which consistently improve clinical outcomes and survival among patients with atrial fibrillation (AF). The main purpose of this study is to identify problems in OAC utilization among hospitalized patients with AF in China. Methods:. Using data from the Improving Care for Cardiovascular Disease in China-Atrial Fibrillation (CCC-AF) registry, guideline-recommended OAC use in eligible patients was assessed. Results:. A total of 52,530 patients with non-valvular AF were enrolled from February 2015 to December 2019, of whom 38,203 were at a high risk of stroke, 9717 were at a moderate risk, and 4610 were at a low risk. On admission, only 20.0% (6075/30,420) of patients with a diagnosed AF and a high risk of stroke were taking OAC. The use of pre-hospital OAC on admission was associated with a lower risk of new-onset ischemic stroke/transient ischemic attack among the diagnosed AF population (adjusted odds ratio: 0.54, 95% confidence interval: 0.43–0.68; P
Document Type: article in journal/newspaper
Language: English
Relation: http://journals.lww.com/10.1097/CM9.0000000000002915; https://doaj.org/toc/0366-6999; https://doaj.org/toc/2542-5641; https://doaj.org/article/4ea87ad6bab34a21aa72bbf6a08b2930
DOI: 10.1097/CM9.0000000000002915
Availability: https://doi.org/10.1097/CM9.0000000000002915; https://doaj.org/article/4ea87ad6bab34a21aa72bbf6a08b2930
Accession Number: edsbas.769F8DA4
Database: BASE