| Title: |
The association between resting heart rate, cardiovascular disease and mortality: Evidence from 112,680 men and women in 12 cohorts |
| Authors: |
M Woodward; R Webster; Y Murakami; F Barzi; TH Lam; X Fang; I Suh; GD Batty; Rachel Huxley; A Rodgers |
| Publication Year: |
2014 |
| Subject Terms: |
Cardiovascular medicine and haematology not elsewhere classified; Clinical sciences not elsewhere classified; Resting heart rate; myocardial infarction; stroke; heart failure; Asia; Australia; mortality; cardiovascular disease; coronary heart disease |
| Description: |
Background: Multiple studies have examined the relationship between heart rate and mortality; however, there are discrepancies in results. Our aim was to describe the relationship between resting heart rate (RHR) and both major cardiovascular (CV) outcomes, as well as all-cause mortality in the Asia-Pacific region. Design and methods: Individual data from 112,680 subjects in 12 cohort studies were pooled and analysed using Cox models, stratified by study and sex, and adjusted for age and systolic blood pressure. Results: During a mean 7.4 years follow-up, 6086 deaths and 2726 fatal or nonfatal CVevents were recorded. There was a continuous, increasing association between having a RHR above approximately 65 beats/min and the risk of both CV and all-cause mortality, yet there was no evidence of associations below this threshold. The hazard ratio (95% CI) comparing the extreme quarters of RHR (80 v |
| Document Type: |
article in journal/newspaper |
| Language: |
unknown |
| Relation: |
http://hdl.handle.net/10536/DRO/DU:30131846; https://figshare.com/articles/journal_contribution/The_association_between_resting_heart_rate_cardiovascular_disease_and_mortality_Evidence_from_112_680_men_and_women_in_12_cohorts/20737471 |
| Availability: |
http://hdl.handle.net/10536/DRO/DU:30131846; https://figshare.com/articles/journal_contribution/The_association_between_resting_heart_rate_cardiovascular_disease_and_mortality_Evidence_from_112_680_men_and_women_in_12_cohorts/20737471 |
| Rights: |
All Rights Reserved |
| Accession Number: |
edsbas.77CF482D |
| Database: |
BASE |