| Title: |
Single Hamstring Tendon Graft using Suspensory Adjustable Button Fixation for Anterior Cruciate Ligament Reconstruction Results in Significantly Lower MRI Graft Signal at both 6 and 12 months: Results from a Subgroup of the DOSTAR Randomised Controlled Trial |
| Authors: |
D’Alessandro, Peter; O’Brien, Stephanie; Davies, Peter; Mayne, Alistair; Malik, Shahbaz; Greensmith, Thomas; Lawless, Adam; Ebert, Jay; Edwards, Peter |
| Source: |
Orthopaedic Journal of Sports Medicine ; volume 14, issue 1_suppl1 ; ISSN 2325-9671 2325-9671 |
| Publisher Information: |
SAGE Publications |
| Publication Year: |
2026 |
| Description: |
Objectives: Hamstring harvest for anterior cruciate ligament reconstruction (ACLr) has been associated with reduced hamstring strength, donor site pain and muscle strains after return to sport. Traditional hamstring grafts require two tendons (DT) to be harvested to achieve a graft of sufficient length and diameter, but newer techniques allow for a shorter, broad single tendon (ST) graft using adjustable button fixation. Magnetic resonance imaging (MRI) analysis of ACLr grafts has previously been used as a proxy for healing and integration of the graft. The MRI signal characteristics of single tendon/adjustable button vs dual tendon/screw graft constructs has not previously been established. Methods: In this double blinded prospective randomised controlled trial (RCT) (registered as a clinical trial with the Australia New Zealand Clinical Trials Registry (ACTRN12620000927921)) patients were recruited and randomised a priori into a single tendon (ST) or a dual tendon (DT) group for ACLR. All anaesthetic and surgical techniques were uniform between the groups aside from graft construct and tibial fixation (Screw for the DT Group, Adjustable Button for the ST Group). Patients underwent MRI analysis using a single 3T MRI scanner (Siemens, Dusseldorf) using a specialised uniform T1 weighted scanning protocol at 6 months and 12 months. MRI signal was measured at multiple regions of interest, with lower signal indicative of better healing and expressed as the signal intensity ratio (SIR). Results: Overall, 46 patients (ST 20; DT 26) were assessed at 6 months post-surgery, and 37 patients (ST 17; DT 21) were assessed at 12 months. No significant group differences (P>0.05) were observed in demographics (age, sex, height and body mass) or surgical characteristics (concomitant meniscal repairs and lateral extra-articular tenodeses). In the ST/Adjustable Button group, the median SIR was 1.7 (SD 0.9) at 6 months and median 1.5 (SD 0.6) at 12 months. In the DT/Screw group, the median SIR was 2.3 (SD 1.2) at 6 months and ... |
| Document Type: |
article in journal/newspaper |
| Language: |
English |
| DOI: |
10.1177/2325967125s00332 |
| DOI: |
10.1177/2325967125S00332 |
| Availability: |
https://doi.org/10.1177/2325967125s00332; https://journals.sagepub.com/doi/pdf/10.1177/2325967125S00332 |
| Rights: |
https://creativecommons.org/licenses/by-nc-nd/4.0/ ; https://journals.sagepub.com/page/policies/text-and-data-mining-license |
| Accession Number: |
edsbas.78039BB0 |
| Database: |
BASE |