| Title: |
Abstract 10193: Association of Inflammation with Decreased Myocardial Function in Covid Patients with Shock |
| Authors: |
Hollenberg, Steven M; Fata, Matthew; Klinkhammer, Brent; Gayed, Noha; Glotzer, Taya; Go, Ronaldo; Gourna-Paleoudis, Elli; Landers, David; Jamal, Sameer; Safi, Lucy; Shah, Neel; Shah, Roshan; Tancredi, Jana; Turi, Zoltan; Parrillo, Joseph E |
| Source: |
Circulation ; volume 144, issue Suppl_1 ; ISSN 0009-7322 1524-4539 |
| Publisher Information: |
Ovid Technologies (Wolters Kluwer Health) |
| Publication Year: |
2021 |
| Description: |
Introduction: The response to COVID infection has been associated with intense inflammation, and some patients have cardiac involvement. In a group of patients with COVID infection and shock whose ventricular function was characterized by echocardiography, we examined the relationship between levels of ferritin, an inflammatory marker that is elevated in COVID, and LV ejection fraction (EF). Methods: Of 1275 patients hospitalized with COVID pneumonia, 215 had shock requiring vasopressors. 162 had echocardiography to assess ventricular function and stroke volume. EF was measured using Simpson’s rule and stroke volume (SV) by Doppler. Patients were divided into groups with low or preserved EF ( EF L or EF P , cutoff <e45%), and low or normal cardiac index, (CI, CI L or CI N , cutoff ≤<e2.2 L/min/m 2 ). Ferritin within 7 days of the echo was available in 147/162 patients. We examined the association between ferritin levels and ejection fraction. Results: Mean age was 66.7, EF 58.7±13.9; CI 2.41±0.89 L/min/m 2 , ferritin 3036±2318 ng/mL (normal |
| Document Type: |
article in journal/newspaper |
| Language: |
English |
| DOI: |
10.1161/circ.144.suppl_1.10193 |
| Availability: |
https://doi.org/10.1161/circ.144.suppl_1.10193 |
| Accession Number: |
edsbas.7841857 |
| Database: |
BASE |